Sleep disorders, despite being very frequent in adults with Down syndrome (DS), are often
overlooked due to a lack of awareness by families and physicians and the absence of …

Individuals with Down syndrome present many clinical characteristics, such as metabolic,
endocrine, anatomic and neurologic dysfunctions, that contribute to the physiopathology of …

Importance Patients with Down syndrome have a high incidence of persistent obstructive
sleep apnea (OSA) and limited treatment options. Upper airway hypoglossal stimulation has …

Hypoglossal nerve stimulation (HGNS) has evolved as a novel and effective therapy for
patients with moderate-to-severe obstructive sleep apnea. Despite positive published …

Background Down syndrome (DS) population has a very high prevalence of obstructive
sleep apnoea (OSA), but this remains underdiagnosed. Hence, we aimed to evaluate …

Hypoglossal nerve stimulation (HNS) has been shown to be a safe alternative in the
treatment of moderate-to-severe obstructive sleep apnea (OSA). A recent meta-analysis of …

Objectives/Hypothesis Patients with Down syndrome have a high incidence of obstructive
sleep apnea (OSA) and limited treatment options. Hypoglossal stimulation has shown …

Down syndrome (DS) is the most common chromosomal abnormality, and the usual quoted
annual incidence is 1 in 700–800 live births worldwide. Sleep problems, and especially …

Abstract Purpose of Review We performed a narrative review of the current knowledge in
epidemiology, mechanisms, clinical presentation, and treatment of sleep disorders in adults …

Importance There are many features of Down syndrome that prompt referral to an
otolaryngologist. As the lifetime prevalence and life expectancy of individuals with Down …