Mechanisms of cancer cell death induction by paclitaxel: an updated review
S Zhao, Y Tang, R Wang, M Najafi - Apoptosis, 2022 - Springer
Chemoresistance of cancer cells is a major problem in treating cancer. Knowledge of how
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …
cancer cells may die or resist cancer drugs is critical to providing certain strategies to …
BCS class IV drugs: Highly notorious candidates for formulation development
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …
exhibit many characteristics that are problematic for effective oral and per oral delivery …
Milk-derived exosomes for oral delivery of paclitaxel
In this report milk-derived exosomes have been investigated for oral delivery of the
chemotherapeutic drug paclitaxel (PAC) as an alternative to conventional iv therapy for …
chemotherapeutic drug paclitaxel (PAC) as an alternative to conventional iv therapy for …
Emerging research and clinical development trends of liposome and lipid nanoparticle drug delivery systems
JC Kraft, JP Freeling, Z Wang, RJY Ho - Journal of pharmaceutical …, 2014 - Elsevier
Liposomes are spherical-enclosed membrane vesicles mainly constructed with lipids. Lipid
nanoparticles are loaded with therapeutics and may not contain an enclosed bilayer. The …
nanoparticles are loaded with therapeutics and may not contain an enclosed bilayer. The …
Current approaches in lipid-based nanocarriers for oral drug delivery
M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …
Polymeric micelles and alternative nanonized delivery vehicles for poorly soluble drugs
Y Lu, K Park - International journal of pharmaceutics, 2013 - Elsevier
Poorly soluble drugs often encounter low bioavailability and erratic absorption patterns in
the clinical setting. Due to the rising number of compounds having solubility issues, finding …
the clinical setting. Due to the rising number of compounds having solubility issues, finding …
Oral delivery of anticancer drugs: challenges and opportunities
The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …
significance of oral delivery in cancer therapeutics has been highlighted which principally …
Coexistence of passive and carrier-mediated processes in drug transport
K Sugano, M Kansy, P Artursson, A Avdeef… - Nature reviews Drug …, 2010 - nature.com
The permeability of biological membranes is one of the most important determinants of the
pharmacokinetic processes of a drug. Although it is often accepted that many drug …
pharmacokinetic processes of a drug. Although it is often accepted that many drug …
Pharmaceutical nanotechnology for oral delivery of anticancer drugs
Oral chemotherapy is an important topic in the 21st century medicine, which may radically
change the current regimen of chemotherapy and greatly improve the quality of life of the …
change the current regimen of chemotherapy and greatly improve the quality of life of the …
Lipid nanocapsules: a new platform for nanomedicine
NT Huynh, C Passirani, P Saulnier, JP Benoît - International journal of …, 2009 - Elsevier
Nanomedicine, an emerging new field created by the fusion of nanotechnology and
medicine, is one of the most promising pathways for the development of effective targeted …
medicine, is one of the most promising pathways for the development of effective targeted …