Chromatin insulators: regulatory mechanisms and epigenetic inheritance
AM Bushey, ER Dorman, VG Corces - Molecular cell, 2008 - cell.com
Enhancer-blocking insulators are DNA elements that disrupt the communication between a
regulatory sequence, such as an enhancer or a silencer, and a promoter. Insulators …
regulatory sequence, such as an enhancer or a silencer, and a promoter. Insulators …
[HTML][HTML] Chromatin insulators and long-distance interactions in Drosophila
O Kyrchanova, P Georgiev - FEBS letters, 2014 - Elsevier
Data on long-distance enhancer-mediated activation of gene promoters and complex
regulation of gene expression by multiple enhancers have prompted the hypothesis that the …
regulation of gene expression by multiple enhancers have prompted the hypothesis that the …
The yellow gene influences Drosophila male mating success through sex comb melanization
Drosophila melanogaster males perform a series of courtship behaviors that, when
successful, result in copulation with a female. For over a century, mutations in the yellow …
successful, result in copulation with a female. For over a century, mutations in the yellow …
Convergence of topological domain boundaries, insulators, and polytene interbands revealed by high-resolution mapping of chromatin contacts in the early …
High-throughput assays of three-dimensional interactions of chromosomes have shed
considerable light on the structure of animal chromatin. Despite this progress, the precise …
considerable light on the structure of animal chromatin. Despite this progress, the precise …
Chromatin structure and the regulation of gene expression: the lessons of PEV in Drosophila
JR Girton, KM Johansen - Advances in genetics, 2008 - Elsevier
Position‐effect variegation (PEV) was discovered in 1930 in a study of X‐ray‐induced
chromosomal rearrangements. Rearrangements that place euchromatic genes adjacent to a …
chromosomal rearrangements. Rearrangements that place euchromatic genes adjacent to a …
[HTML][HTML] Architectural proteins, transcription, and the three-dimensional organization of the genome
C Cubeñas-Potts, VG Corces - FEBS letters, 2015 - Elsevier
Architectural proteins mediate interactions between distant sequences in the genome. Two
well-characterized functions of architectural protein interactions include the tethering of …
well-characterized functions of architectural protein interactions include the tethering of …
Genome-wide mapping of boundary element-associated factor (BEAF) binding sites in Drosophila melanogaster links BEAF to transcription
Insulator elements play a role in gene regulation that is potentially linked to nuclear
organization. Boundary element-associated factors (BEAFs) 32A and 32B associate with …
organization. Boundary element-associated factors (BEAFs) 32A and 32B associate with …
Mechanisms and proteins involved in long-distance interactions
O Maksimenko, P Georgiev - Frontiers in genetics, 2014 - frontiersin.org
Due to advances in genome-wide technologies, consistent distant interactions within
chromosomes of higher eukaryotes have been revealed. In particular, it has been shown …
chromosomes of higher eukaryotes have been revealed. In particular, it has been shown …
Chromatin insulators: a role in nuclear organization and gene expression
J Yang, VG Corces - Advances in cancer research, 2011 - Elsevier
Chromatin insulators are DNA–protein complexes with broad functions in nuclear biology.
Based on the ability of insulator proteins to interact with each other, it was originally found …
Based on the ability of insulator proteins to interact with each other, it was originally found …
Functional requirements for Fab-7 boundary activity in the bithorax complex
Chromatin boundaries are architectural elements that determine the three-dimensional
folding of the chromatin fiber and organize the chromosome into independent units of …
folding of the chromatin fiber and organize the chromosome into independent units of …