Diagnostic criteria and contributors to Gilbert's syndrome

KH Wagner, RG Shiels, CA Lang… - Critical reviews in …, 2018 - Taylor & Francis
Hyperbilirubinemia is a well-known condition in the clinical setting; however, the causes of
elevated serum bilirubin are diverse, as are the clinical ramifications of this condition. For …

Gilbert´ s syndrome revisited

L Vítek, C Tiribelli - Journal of hepatology, 2023 - Elsevier
Gilbert´ s syndrome, also known as benign hyperbilirubinemia, was described more than
100 years ago. It has usually been considered a physiological abnormality characterized by …

Bilirubin, platelet activation and heart disease: a missing link to cardiovascular protection in Gilbert's syndrome?

AR Kundur, I Singh, AC Bulmer - Atherosclerosis, 2015 - Elsevier
Gilbert's syndrome (GS) is a relatively common condition, inducing a benign, non-hemolytic,
unconjugated hyperbilirubinemia. Gilbert's Syndrome is associated with mutation in the …

G ilbert's syndrome and the risk of death: A population‐based cohort study

LJ Horsfall, I Nazareth, SP Pereira… - … of gastroenterology and …, 2013 - Wiley Online Library
Background and Aims G ilbert's syndrome is a common familial hyperbilirubinemia that may
reduce the risk of various age‐related diseases because of the antioxidant properties of …

Hyperbilirubinemia as a predictor for appendiceal perforation: a systematic review

J Burcharth, HC Pommergaard… - … Journal of Surgery, 2013 - journals.sagepub.com
Background and Aims: Delayed or wrong diagnosis in patients with appendicitis can result
in perforation and consequently increased morbidity and mortality. Serum bilirubin may be a …

Prevalence of Clinically Relevant UGT1A Alleles and Haplotypes in African Populations

LJ Horsfall, D Zeitlyn, A Tarekegn… - Annals of human …, 2011 - Wiley Online Library
Variation of a short (TA) n repeat sequence (rs8175347) covering the TATA box of UGT1A1
(UDP‐glucuronosyltransferase1A1) is associated with hyperbilirubinaemia (Gilbert's …

Mildly elevated unconjugated bilirubin is associated with reduced platelet activation-related thrombogenesis and inflammation in Gilbert's syndrome

AR Kundur, AB Santhakumar, AC Bulmer, I Singh - Platelets, 2017 - Taylor & Francis
Gilbert's syndrome (GS) is associated with a mild unconjugated hyperbilirubinemia,
increased circulating antioxidant capacity, and reduced cardiovascular disease (CVD) risk …

Potential Cardiovascular Risk Protection of Bilirubin in End‐Stage Renal Disease Patients under Hemodialysis

M Sameiro-Faria, M Kohlova, S Ribeiro… - BioMed Research …, 2014 - Wiley Online Library
We evaluated the potential cardiovascular risk protection of bilirubin in hemodialysis (HD)
patients. An enlarged set of studies were evaluated in 191 HD patients, including …

Bilirubin dependence on UGT1A1 polymorphisms, hemoglobin, fasting time and body mass index

C Rodrigues, E Costa, E Vieira, R Santos… - The American journal of …, 2012 - Elsevier
In humans, bilirubin levels are influenced by different factors. This study evaluates how
several nongenetic causes and the genetic UGT1A1 polymorphisms contribute for bilirubin …

Carbon monoxide breath test assessment of mild hemolysis in Gilbert's syndrome

LL Kang, YJ Ma, HD Zhang - Medicine, 2020 - journals.lww.com
Background: Mild hemolysis is difficult to determinate by traditional methods, and its role in
Gilbert's syndrome (GS) is unclear. The main aims were to inspect the erythrocyte (RBC) …