Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Stem cell–based approaches have received much hype as potential treatments for
neurodegenerative disorders. Indeed, transplantation of stem cells or their derivatives in …

Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …

Despite the vast improvements of cell therapy in spinal cord injury treatment, no optimum
protocol has been developed for application of neural stem/progenitor cells. In this regard …

Background Umbilical cord mesenchymal stem cells (UCMSCs) have a considerable
advantage and potential in treating for central nervous system diseases and have become a …

Collagen scaffolds possess a three-dimensional porous structure that provides sufficient
space for cell growth and proliferation, the passage of nutrients and oxygen, and the …

Tissue and organ repair still represents a clinical challenge. Tissue engineering and
regenerative medicine (TERM) is an emerging field focused on the development of …

Nanostructured scaffolds recently showed great promise in tissue engineering:
nanomaterials can be tailored at the molecular level and scaffold morphology may more …

Umbilical cord blood-derived mononuclear cell (UCB-MNC) transplants improve recovery in
animal spinal cord injury (SCI) models. We transplanted UCB-MNCs into 28 patients with …

Small direct current (DC) electric fields (EFs) guide neurite growth and migration of rodent
neural stem cells (NSCs). However, this could be species dependent. Therefore, it is critical …