The Yin and Yang of exosome isolation methods: conventional practice, microfluidics, and commercial kits

SZ Shirejini, F Inci - Biotechnology Advances, 2022 - Elsevier
Exosomes are a subset of extracellular vesicles released from various cells, and they can be
found in different bodily fluids. Exosomes have been utilized as biomarkers to diagnose …

[HTML][HTML] Exosomes and extracellular vesicles: Rethinking the essential values in cancer biology

A Yokoi, T Ochiya - Seminars in cancer biology, 2021 - Elsevier
Extracellular vesicles (EVs) such as exosomes are released by all living cells and contain
diverse bioactive molecules, including nucleic acids, proteins, lipids, and metabolites …

Organically derived exosomes as carriers of anticancer drugs and imaging agents for cancer treatment

A Srivastava, S Rathore, A Munshi… - Seminars in cancer biology, 2022 - Elsevier
Extracellular vesicles (EVs), is the umbrella term used for different types of vesicles
produced by the cells, among which exosomes form the largest group. Exosomes perform …

Tumor-targeted exosomes for delivery of anticancer drugs

R Raguraman, D Bhavsar, D Kim, X Ren, V Sikavitsas… - Cancer letters, 2023 - Elsevier
Exosomes are small phospholipid bilayer vesicles that are naturally produced by all living
cells, both prokaryotes and eukaryotes. The exosomes due to their unique size, reduced …

Trends in research on exosomes in cancer progression and anticancer therapy

D Sinha, S Roy, P Saha, N Chatterjee, A Bishayee - Cancers, 2021 - mdpi.com
Simple Summary Intensive research in the field of cancer biology has discovered a unique
mode of interplay between cells via extracellular bioactive vesicles called exosomes …

Cancer: a mirrored room between tumor bulk and tumor microenvironment

P Hernández-Camarero, E López-Ruiz… - Journal of Experimental …, 2021 - Springer
It has been well documented that the tumor microenvironment (TME) plays a key role in the
promotion of drug resistance, the support of tumor progression, invasiveness, metastasis …

Communication is key: extracellular vesicles as mediators of infection and defence during host–microbe interactions in animals and plants

H U. Stotz, D Brotherton, J Inal - FEMS microbiology reviews, 2022 - academic.oup.com
Extracellular vesicles (EVs) are now understood to be ubiquitous mediators of cellular
communication. In this review, we suggest that EVs have evolved into a highly regulated …

EVs and bioengineering: from cellular products to engineered nanomachines

S Villata, M Canta, V Cauda - International journal of molecular sciences, 2020 - mdpi.com
Extracellular vesicles (EVs) are natural carriers produced by many different cell types that
have a plethora of functions and roles that are still under discovery. This review aims to be a …

Exosomes as drug delivery vehicle and contributor of resistance to anticancer drugs

M Chinnappan, A Srivastava, N Amreddy, M Razaq… - Cancer letters, 2020 - Elsevier
Exosomes are small membranous vesicles implicated in intercellular signalling. Through
their uncanny ability to carry and deliver donor cellular cargo (biomolecules) to target cells …

Extracellular vesicles as natural therapeutic agents and innate drug delivery systems for cancer treatment: Recent advances, current obstacles, and challenges for …

M Pirisinu, TC Pham, DX Zhang, TN Hong… - Seminars in Cancer …, 2022 - Elsevier
As cancer poses a significant threat to the well-being of humans on a global scale, many
researchers have embarked on the search for effective anticancer therapeutic agents. In …