Aducanumab—hope or disappointment for Alzheimer's disease

K Wojtunik-Kulesza, M Rudkowska… - International journal of …, 2023 - mdpi.com
In June 2021, the world was informed about a new drug for Alzheimer's disease approved
by the FDA. Aducanumab (BIIB037, ADU), being a monoclonal antibody IgG1, is the newest …

Towards computational solutions for precision medicine based big data healthcare system using deep learning models: A review

R Thirunavukarasu, R Gnanasambandan… - Computers in Biology …, 2022 - Elsevier
The emergence of large-scale human genome projects, advances in DNA sequencing
technologies, and the massive volume of electronic medical records [EMR] shift the …

The role of Chinese medicine in health maintenance and disease prevention: application of constitution theory

L Li, H Yao, J Wang, Y Li, Q Wang - The American journal of …, 2019 - World Scientific
Traditional Chinese medicine (TCM) has guided health maintenance and disease treatment
for thousands of years and has been widely used in many countries around the world. TCM …

A review on omics-based biomarkers discovery for Alzheimer's disease from the bioinformatics perspectives: statistical approach vs machine learning approach

MS Tan, PL Cheah, AV Chin, LM Looi… - Computers in biology and …, 2021 - Elsevier
Alzheimer's Disease (AD) is a neurodegenerative disease that affects cognition and is the
most common cause of dementia in the elderly. As the number of elderly individuals …

[HTML][HTML] The road to precision medicine: Eliminating the “One Size Fits All” approach in Alzheimer's disease

T Behl, I Kaur, A Sehgal, S Singh, A Albarrati… - Biomedicine & …, 2022 - Elsevier
The expeditious advancement of Alzheimer's Disease (AD) is a threat to the global
healthcare system, that is further supplemented by therapeutic failure. The prevalence of this …

The future of precision medicine in the cure of Alzheimer's disease

A Arafah, S Khatoon, I Rasool, A Khan, MA Rather… - Biomedicines, 2023 - mdpi.com
This decade has seen the beginning of ground-breaking conceptual shifts in the research of
Alzheimer's disease (AD), which acknowledges risk elements and the evolving wide …

[HTML][HTML] Extracellular vesicles and Alzheimer's disease in the novel era of Precision Medicine: Implications for disease progression, diagnosis and treatment

P Gomes, F Tzouanou, K Skolariki… - Experimental …, 2022 - Elsevier
Extracellular vesicles (EVs), secreted membranous nano-sized particles, are critical
intercellular messengers participating in nervous system homeostasis, while recent …

Female specific risk factors for the development of Alzheimer's disease neuropathology and cognitive impairment: Call for a precision medicine approach

C Udeh-Momoh, T Watermeyer - Ageing Research Reviews, 2021 - Elsevier
Alzheimer's disease (AD) includes a long asymptomatic stage, which precedes the formal
diagnosis of dementia. AD biomarker models provide a framework for precision medicine …

Physical exercise as personalized medicine for dementia prevention?

P Müllers, M Taubert, NG Müller - Frontiers in Physiology, 2019 - frontiersin.org
Accumulating evidence mainly from observational studies supports the notion that lifestyle
factors such as regular physical activity can modulate potential risk factors of dementia …

A systematic review on predictors of working memory training responsiveness in healthy older adults: Methodological challenges and future directions

A Ophey, M Roheger, AK Folkerts, N Skoetz… - Frontiers in aging …, 2020 - frontiersin.org
Background: Research on predictors of working memory training responsiveness, which
could help tailor cognitive interventions individually, is a timely topic in healthy aging …