Ischemic stroke after cerebral artery occlusion is one of the major causes of chronic disability
worldwide. Interleukins (ILs) play a bidirectional role in ischemic stroke through information …

Interleukin-1 (IL-1) family cytokines are key signaling molecules in both the innate and
adaptive immune systems, mediating inflammation in response to a wide range of stimuli …

The extracellular forms of the IL‐1 cytokines are active through binding to specific receptors
on the surface of target cells. IL‐1 ligands bind to the extracellular portion of their ligand …

Members of the extended interleukin-1 (IL-1) cytokine family, such as IL-1, IL-18, IL-33, and
IL-36, play a pivotal role in the initiation and amplification of immune responses. However …

Abstract The interleukin (IL)-1 family of cytokines comprises 11 members, including 7 pro-
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …

Psoriasis is a common inflammatory skin disease with an incompletely understood etiology.
The disease is characterized by red, scaly and well-demarcated skin lesions formed by the …

Probiotics such as Lactobacillus and Bifidobacterium have been successfully used to
promote growth and prevent diseases. Previous reports have demonstrated that Bacillus …

Background Generalized pustular psoriasis is a life-threatening disease of unknown cause.
It is characterized by sudden, repeated episodes of high-grade fever, generalized rash, and …

The IL-1 cytokine family comprises 11 members (7 ligands with agonist activity, 3 receptor
antagonists and 1 anti-inflammatory cytokine) and is recognised as a key mediator of …

The function of interleukin 37 (IL-37; formerly IL-1 family member 7) has remained elusive.
Expression of IL-37 in macrophages or epithelial cells almost completely suppressed …