Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Multiple sclerosis (MS) is a central nervous system (CNS) disorder characterized by
inflammation, demyelination, and neurodegeneration. Emerging research suggests that …

Aging is associated with impaired cognition and memory and increased susceptibility to
neurodegenerative disorders. Physical exercise is neuroprotective; however, the major …

Physical exercise is a promising rehabilitative strategy for acute ischemic stroke. Preclinical
trials suggest that exercise restores cerebral blood circulation and re-establishes the blood …

During strenuous exercise there is a progressive increase in lactate uptake and metabolism
into the brain as workload and plasma lactate levels increase. Although it is now widely …

[Methods] In this study, restraint stress with or without voluntary wheel running was
performed for mice housed in individual cages. A total of 21 ICR male mice were assigned …

Introduction Drug addiction is associated with disruption of a multitude of biomarkers in
various brain regions, particularly in the reward centre. The most pronounced are …

Although it is well known that physical training ameliorates brain oxidative function after
injuries by enhancing the levels of neurotrophic factors and oxidative status, there is little …

Pregnancy is a critical period for brain metabolic programming, being affected by individual
environment, such as nutrition, stress, and physical exercise. In this context, we previously …

Previous studies have demonstrated that exercise facilitates recovery from ischemia.
However, the mechanisms need to be further elucidated. The current investigation was …