Although considerable effort and progress has been made in the search for new anticancer
drugs and treatments in the last several decades, cancer remains a major public health …

Due to taxonomic positions and special living environments, marine organisms produce
secondary metabolites that possess unique structures and biological activities. This review …

Two new nonadride derivatives, namely, talarodrides G and H (1 and 2), and one new
depsidone derivative, botryorhodine K (3), together with a known nonadride analogue (4) …

Three new oxygen-bridged cyclooctadiene containing compounds, 5–7, phomoxydienes A–
C, and two new dothiorelones I (8) and J (9), together with 10 known compounds were …

Context: Endophytic fungi, being a prolific source of bioactive secondary metabolites, are of
great interest for natural product discovery. Objective: Isolation and partial characterization …

A series of inhibitors of NF-κB based on ursolic acid (UA) derivatives containing long-chain
diamine moieties were designed and synthesized as well as evaluated the antitumor effects …

Endophytes fungi have been widely bioprospected to find new drugs and drug leads
including antimicrobial agents and antifungals. However, an important role in host plant …

Mycoepoxydiene (MED) is a polyketide isolated from the marine fungal Diaporthe sp. HLY-1
associated with mangroves. Although MED has been shown to have various biological …

Using 126 endogenous lichen fungus (ELF) extracts, inhibitory activities against monoamine
oxidases (MAOs) and cholinesterases (ChEs) were evaluated. Among them, extract ELF29 …

Upregulation of glycolysis and the pentose phosphate pathway (PPP) is a major
characteristic of the metabolic reprogramming of cancer and provides cancer cells with …