There is currently an increased interest in understanding the role of the tumor
microenvironment (TME) in tumor growth and progression. In this context the role of integrins …

Aims Crosstalk between fibroblasts and cardiomyocytes (CMs) plays a critical role in cardiac
remodelling during heart failure (HF); however, the underlying molecular mechanisms …

The resistance to anoikis plays a critical role in the metastatic progression of various types of
malignancies, including gastric cancer (GC). Nevertheless, the precise mechanism behind …

Cardiac fibrosis is a severe condition with limited therapeutic options and often occurs in
chronic cardiovascular diseases such as hypertension and myocardial infarction. There is …

Background Cancer metastasis and recurrence remain major challenges in renal carcinoma
patient management. There are limited biomarkers to predict the metastatic probability of …

Introduction: Kidney transplantation (KT) has surpassed dialysis as the optimal therapy for
end-stage kidney disease. Yet, most patients could suffer from a slow but continuous …

Objectives Integrin subunit beta-like 1 (ITGBL1), a member of the epidermal growth factor
(EGF)-like protein family, encodes a beta integrin-related protein that is mainly associated …

Endometriosis is a common cause of endometrial-type mucosa outside the uterine cavity
with symptoms such as painful periods, chronic pelvic pain, pain with intercourse and …

Ovarian cancer (OC) is usually diagnosed late due to its nonspecific symptoms and lack of
reliable tools for early diagnostics and screening. OC studies concentrate on the search for …