Emerging insights into pyrazoline motifs: A comprehensive exploration of biological mechanisms and prospects for future advancements
The prevalence of cancer and neurodegenerative diseases, such as Alzheimer's and
Parkinson's, continues to rise worldwide, presenting a significant health burden. Despite …
Parkinson's, continues to rise worldwide, presenting a significant health burden. Despite …
Synthesis of benzalacetophenone-based isoxazoline and isoxazole derivatives
The demand for natural product-based drugs with less cost and efficient procedures has
become a challenge for researchers. Benzalacetophenone is a natural product-based …
become a challenge for researchers. Benzalacetophenone is a natural product-based …
Synthesis, nonlinear optical activity, solvents effect, β-cyclodextrin effect, and cytotoxic activity on skin fibroblast and breast cancer cell lines of a new chalcone …
V Meenatchi, S Kim, SY Won, K Buvaneswari… - … Acta Part A: Molecular …, 2025 - Elsevier
The use of small organic molecules, such as chalcones, for efficient applications as organic
luminescent materials has attracted increasing attention owing to their interesting optical …
luminescent materials has attracted increasing attention owing to their interesting optical …
Crystal, Hirshfeld, ADMET, drug-like and anticancer study of some newly synthesized imidazopyridine containing pyrazoline derivatives
S Kuthyala, M Hanumanthappa, SM Kumar… - Journal of Molecular …, 2019 - Elsevier
To steer the selection of a potent drug, computer models have been fostered as a valid
alternative to reduce pharmacokinetics related failure. The present study mainly focuses on …
alternative to reduce pharmacokinetics related failure. The present study mainly focuses on …
Three anticancer Pt complexes with glycine derivatives: synthesis, bioactivity on MCF-7 cell line, ADME prediction, DFT, MEP, and molecular docking
M Eslami Moghadam, A Jafari… - Journal of the Iranian …, 2021 - Springer
For investigating reduction of side effects of commercial anticancer drugs, such as cisplatin,
three new platinum complexes with glycine derivatives and the formula of [Pt (R-amine) 2 (R …
three new platinum complexes with glycine derivatives and the formula of [Pt (R-amine) 2 (R …
Molecular docking, synthesis and ADME studies of new pyrazoline derivatives as potential anticancer agents
AK Wabdan, MF Mahdi, AK Khan - Egyptian Journal of Chemistry, 2021 - journals.ekb.eg
Cancer is a significant worldwide public health issue. The adverse effects of anticancer
chemotherapies still compromise the quality of life of patients. To identify new potential …
chemotherapies still compromise the quality of life of patients. To identify new potential …
Performance and photoresponse characterizations of pyrimidine quinolone carboxylate derivatives films-based heterojunction devices
In this investigation, novel pyrimido quinolone derivative carboxylate was produced. For the
first time, we attempted to obtain, a high-quality thin film of HBPQC using the thermal …
first time, we attempted to obtain, a high-quality thin film of HBPQC using the thermal …
COX-2 Enzyme Inhibitors Study and Efficacy Pharmacokinetic by Molecular Docking for some New Heterocyclic Rings Driver from Levofloxacin Drug
MI Khalaf - Russian Journal of Bioorganic Chemistry, 2023 - Springer
Assay methods using cyclooxygenase fluorescence inhibitors and the standard drug
levofloxacin were used to determine the anti-inflammatory profile of Triazole, Triazine …
levofloxacin were used to determine the anti-inflammatory profile of Triazole, Triazine …
Oxazole, Oxadiazole, Isoxazoline and Oxazoline Derivatives as Anti-Inflammatory Agents
N Sharma - Heterocyclic Anti-Inflammatory Agents: A Guide …, 2024 - benthamdirect.com
Oxygen and Nitrogen containing five-membered heterocyclic compounds have been the
target of intense investigation in the last two decades to discover potent biologically active …
target of intense investigation in the last two decades to discover potent biologically active …
[PDF][PDF] Synthesis, Anti-Inflammatory Activity and Molecular Docking Studies of 1, 4, 5, 6-Tetrahydropyrimidine-2-Carboxamides
VY Horishny, PV Zadorozhnii, IV Horishnia… - Pharmaceutical …, 2020 - ps.tbzmed.ac.ir
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly
used drugs in the world. The widespread use of NSAIDs is associated with a number of …
used drugs in the world. The widespread use of NSAIDs is associated with a number of …