Type 2 diabetes mellitus and cardiovascular disease: genetic and epigenetic links
S De Rosa, B Arcidiacono, E Chiefari… - Frontiers in …, 2018 - frontiersin.org
Type 2 diabetes mellitus (DM) is a common metabolic disorder predisposing to diabetic
cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to …
cardiomyopathy and atherosclerotic cardiovascular disease (CVD), which could lead to …
MicroRNAs and long non-coding RNAs in the pathophysiological processes of diabetic cardiomyopathy: emerging biomarkers and potential therapeutics
The epidemic of diabetes mellitus (DM) necessitates the development of novel therapeutic
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
and preventative strategies to attenuate complications of this debilitating disease. Diabetic …
HIF-1, metabolism, and diabetes in the embryonic and adult heart
R Cerychova, G Pavlinkova - Frontiers in Endocrinology, 2018 - frontiersin.org
The heart is able to metabolize any substrate, depending on its availability, to satisfy its
energy requirements. Under normal physiological conditions, about 95% of ATP is produced …
energy requirements. Under normal physiological conditions, about 95% of ATP is produced …
Diabetes and cardiovascular disease: inter-relation of risk factors and treatment
Background The diabetes mellitus prevalence is still advancing and increasingly becoming
one of the globally most severe and expensive chronic illnesses. The strong correlation …
one of the globally most severe and expensive chronic illnesses. The strong correlation …
The potential role of platelet-related microRNAs in the development of cardiovascular events in high-risk populations, including diabetic patients: a review
Platelet activation plays a pivotal role in the development and progression of
atherosclerosis, which often leads to potentially fatal ischemic events at later stages of the …
atherosclerosis, which often leads to potentially fatal ischemic events at later stages of the …
Impact of sex differences and diabetes on coronary atherosclerosis and ischemic heart disease
Cardiovascular diseases (CVD) including coronary artery disease (CAD) and ischemic heart
disease (IHD) are the main cause of mortality in industrialized countries. Although it is well …
disease (IHD) are the main cause of mortality in industrialized countries. Although it is well …
Fibroblasts orchestrate cellular crosstalk in the heart through the ECM
Cell communication is needed for organ function and stress responses, especially in the
heart. Cardiac fibroblasts, cardiomyocytes, immune cells and endothelial cells comprise the …
heart. Cardiac fibroblasts, cardiomyocytes, immune cells and endothelial cells comprise the …
Epigenetic Modifications and Non-Coding RNA in Diabetes-Mellitus-Induced Coronary Artery Disease: Pathophysiological Link and New Therapeutic Frontiers
FR Prandi, D Lecis, F Illuminato, M Milite… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus (DM) is a glucose metabolism disorder characterized by chronic
hyperglycemia resulting from a deficit of insulin production and/or action. DM affects more …
hyperglycemia resulting from a deficit of insulin production and/or action. DM affects more …
A literature embedding model for cardiovascular disease prediction using risk factors, symptoms, and genotype information
Accurate prediction of cardiovascular disease (CVD) requires multifaceted information
consisting of not only a patient's medical history, but genomic data, symptoms, lifestyle, and …
consisting of not only a patient's medical history, but genomic data, symptoms, lifestyle, and …
Diabetic cardiomyopathy: the role of microRNAs and long non-coding RNAs
MT Macvanin, Z Gluvic, J Radovanovic… - Frontiers in …, 2023 - frontiersin.org
Diabetes mellitus (DM) is on the rise, necessitating the development of novel therapeutic
and preventive strategies to mitigate the disease's debilitating effects. Diabetic …
and preventive strategies to mitigate the disease's debilitating effects. Diabetic …