Introduction Millions of people worldwide suffer with spasticity related to irreversible damage
to the brain or spinal cord. Typical antecedent events include stroke, traumatic brain injury …

Understanding the relevant biophysical properties of the spinal dura mater is essential to the
design of medical devices that will directly interact with this membrane or influence the …

Objective. Microelectrodes implanted in the central nervous system (CNS) often fail in long
term implants due to the immunological tissue response caused by tethering forces of the …

Introduction The intrathecal space remains underutilized for diagnostic testing, invasive
monitoring or as a pipeline for the delivery of neurological therapeutic agents and devices …

Introduction: Intradural spinal cord stimulation (SCS) may offer significant therapeutic
benefits for those with intractable axial and extremity pain, visceral pain, spasticity …

Introduction The introduction of successful neuromodulation strategies for managing chronic
visceral pain lag behind what is now treatment of choice in refractory chronic back and …

Background It is becoming increasingly important to understand the mechanisms of spinal
cord stimulation (SCS) in alleviating neuropathic pain as novel stimulation paradigms arise …

We have characterized the mechanical compliance of an improved version of the
suspension system used to position the electrode-bearing membrane of an intradural …

Background: Spinal cord stimulation has been in use for decades and is growing as a
therapeutic treatment option. A significant problem arising from the epidural location of the …

We have designed, built, and tested an apparatus used for investigating the biomechanical
response of a novel intradural spinal cord stimulator to the simulated physiological …