Advances and prospects for the Human BioMolecular Atlas Program (HuBMAP)

S Jain, L Pei, JM Spraggins, M Angelo, JP Carson… - Nature cell …, 2023 - nature.com
Abstract The Human BioMolecular Atlas Program (HuBMAP) aims to create a multi-scale
spatial atlas of the healthy human body at single-cell resolution by applying advanced …

Challenges in unsupervised clustering of single-cell RNA-seq data

VY Kiselev, TS Andrews, M Hemberg - Nature Reviews Genetics, 2019 - nature.com
Single-cell RNA sequencing (scRNA-seq) allows researchers to collect large catalogues
detailing the transcriptomes of individual cells. Unsupervised clustering is of central …

ImmPort, toward repurposing of open access immunological assay data for translational and clinical research

S Bhattacharya, P Dunn, CG Thomas, B Smith… - Scientific data, 2018 - nature.com
Immunology researchers are beginning to explore the possibilities of reproducibility, reuse
and secondary analyses of immunology data. Open-access datasets are being applied in …

Tutorial: guidelines for annotating single-cell transcriptomic maps using automated and manual methods

ZA Clarke, TS Andrews, J Atif, D Pouyabahar… - Nature protocols, 2021 - nature.com
Single-cell transcriptomics can profile thousands of cells in a single experiment and identify
novel cell types, states and dynamics in a wide variety of tissues and organisms. Standard …

An integrated expression atlas of miRNAs and their promoters in human and mouse

D De Rie, I Abugessaisa, T Alam, E Arner, P Arner… - Nature …, 2017 - nature.com
MicroRNAs (miRNAs) are short non-coding RNAs with key roles in cellular regulation. As
part of the fifth edition of the Functional Annotation of Mammalian Genome (FANTOM5) …

A census of the lung: CellCards from LungMAP

X Sun, AK Perl, R Li, SM Bell, E Sajti, VV Kalinichenko… - Developmental cell, 2022 - cell.com
The human lung plays vital roles in respiration, host defense, and basic physiology. Recent
technological advancements such as single-cell RNA sequencing and genetic lineage …

A draft network of ligand–receptor-mediated multicellular signalling in human

JA Ramilowski, T Goldberg, J Harshbarger… - Nature …, 2015 - nature.com
Cell-to-cell communication across multiple cell types and tissues strictly governs proper
functioning of metazoans and extensively relies on interactions between secreted ligands …

An atlas of human long non-coding RNAs with accurate 5′ ends

CC Hon, JA Ramilowski, J Harshbarger, N Bertin… - Nature, 2017 - nature.com
Long non-coding RNAs (lncRNAs) are largely heterogeneous and functionally
uncharacterized. Here, using FANTOM5 cap analysis of gene expression (CAGE) data, we …

A promoter-level mammalian expression atlas

Nature, 2014 - nature.com
Regulated transcription controls the diversity, developmental pathways and spatial
organization of the hundreds of cell types that make up a mammal. Using single-molecule …

The GOA database: gene ontology annotation updates for 2015

RP Huntley, T Sawford… - Nucleic acids …, 2015 - academic.oup.com
Abstract The Gene Ontology Annotation (GOA) resource (http://www. ebi. ac. uk/GOA)
provides evidence-based Gene Ontology (GO) annotations to proteins in the UniProt …