Background Adolescence is a critical biological, psychological, and social developmental
stage involving heightened risk for substance use and associated adverse consequences …

Learning Objective: After participating in this activity, learners should be better able to:
Evaluate the rationale for and current evidence supporting medication-assisted treatment of …

Abstract Background The United States (US) is experiencing an ongoing opioid crisis.
Economic burden estimates that describe the impact of the crisis are needed when …

Background & Aims Central neuromodulators (antidepressants, antipsychotics, and other
central nervous system− targeted medications) are increasingly used for treatment of …

Needle syringe programmes and opioid substitution therapy for preventing hepatitis C
transmission in people who inject drugs - Platt, L - 2017 | Cochrane Library Skip to Content …

Importance Retention in addiction treatment is associated with reduced mortality for
individuals with opioid use disorder (OUD). Although clinical trials support use of OUD …

Importance Opioid use disorder (OUD) frequently begins in adolescence and young
adulthood. Intervening early with pharmacotherapy is recommended by major professional …

Background Buprenorphine maintenance treatment has been evaluated in randomised
controlled trials against placebo medication, and separately as an alternative to methadone …

Adolescent substance use is an issue of critical importance to the American public. In 2011,
a nationally representative household survey found that adults rated drug abuse as the …

Background Injecting drug users are vulnerable to infection with HIV and other blood borne
viruses as a result of collective use of injecting equipment as well as sexual behaviour …