miRNAs as potential game-changers in renal cell carcinoma: Future clinical and medicinal uses

MS Elballal, AAM Sallam, AE Elesawy… - … -Research and Practice, 2023 - Elsevier
Renal cell carcinoma (RCC) has the highest mortality rate of all genitourinary cancers, and
its prevalence has grown over time. While RCC can be surgically treated and recurrence is …

Sarcomatoid renal cell carcinoma: biology, natural history and management

KA Blum, S Gupta, SK Tickoo, TA Chan… - Nature Reviews …, 2020 - nature.com
Sarcomatoid dedifferentiation is an uncommon feature that can occur in most histological
subtypes of renal cell carcinomas (RCCs) and carries a decidedly poor prognosis …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

Potential role of selenium in the treatment of cancer and viral infections

AO Rataan, SM Geary, Y Zakharia, YM Rustum… - International journal of …, 2022 - mdpi.com
Selenium has been extensively evaluated clinically as a chemopreventive agent with
variable results depending on the type and dose of selenium used. Selenium species are …

Red Phosphorus Decorated TiO2 Nanorod Mediated Photodynamic and Photothermal Therapy for Renal Cell Carcinoma

C Yang, Y Zhu, D Li, Y Liu, C Guan, X Man, S Zhang… - Small, 2021 - Wiley Online Library
Clear cell renal cell carcinoma (ccRCC) is a serious and tenacious disease. Photodynamic
therapy (PDT) and photothermal therapy (PTT) are effective means of cancer treatment …

Anti-angiogenesis and immunotherapy: novel paradigms to envision tailored approaches in renal cell-carcinoma

A Argentiero, AG Solimando, M Krebs, P Leone… - Journal of Clinical …, 2020 - mdpi.com
Although decision making strategy based on clinico-histopathological criteria is well
established, renal cell carcinoma (RCC) represents a spectrum of biological ecosystems …

miR-124 and miR-203 synergistically inactivate EMT pathway via coregulation of ZEB2 in clear cell renal cell carcinoma (ccRCC)

J Chen, Y Zhong, L Li - Journal of Translational Medicine, 2020 - Springer
Background Clear cell renal cell carcinoma (ccRCC) is one of the most aggressive
urological malignancies. MicroRNAs (miRNAs) are post-transcriptional gene regulators in …

A “Lymphocyte MicroRNA Signature” as predictive biomarker of immunotherapy response and plasma PD-1/PD-L1 expression levels in patients with metastatic renal …

L Incorvaia, D Fanale, G Badalamenti, C Brando… - Cancers, 2020 - mdpi.com
Simple Summary MicroRNAs are small molecules of non-coding RNAs which regulate gene
expression at the post-transcriptional level. Normal miRNA expression and function can be …

Transcription factor and miRNA interplays can manifest the survival of ccRCC patients

S Qin, X Shi, C Wang, P Jin, F Ma - Cancers, 2019 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) still remains a higher mortality rate in worldwide.
Obtaining promising biomakers is very crucial for improving the diagnosis and prognosis of …

Exosomes derived from mesenchymal stem cells curbs the progression of clear cell renal cell carcinoma through T-cell immune response

D Li, F Lin, G Li, F Zeng - Cytotechnology, 2021 - Springer
Exosomes derived from mesenchymal stem cells (MSC-Exo) are effective in modulating
immunity. However, the role of MSC-Exo in clear cell renal cell carcinoma (ccRCC) is …