Abstract Insulin-like growth factor-1 (IGF-1), a pleiotropic polypeptide, plays an essential role
in CNS development and maturation. Glucagon-like peptide-1 (GLP-1) is an endogenous …

ABSTRACT Glucagon-like peptide 1 (GLP-1) is a target for treatment of diabetes; however,
its function in the brain is not well studied. In this systematic review, we aimed to analyze the …

Abstract Glucagon-like peptide-1 (GLP-1) signaling in the brain plays an important role in
the regulation of glucose metabolism, which is impaired in Alzheimer's disease (AD). Here …

Drug repositioning is a revolution breakthrough of drug discovery that presents outstanding
privilege with already safer agents by scanning the existing candidates as therapeutic …

Background Neuroinflammation is a key pathological component of neurodegenerative
disease and is characterized by microglial activation and the secretion of proinflammatory …

Inflammatory processes, including ulcerative colitis (UC), are associated with the increase in
synthesis and release of pro-inflammatory cytokines. The release of these cytokines is …

Abstract Glucagon-like peptide 1 (GLP-1) agonists are among the agents that can be used to
treat type 2 diabetes mellitus, and they have also been reported to have neuroprotective …

Aims In this narrative review, we have analyzed and synthesized current studies relating to
the effects of anti-diabetic drugs on traumatic brain injury (TBI) complications. Methods …

Traumatic brain injury (TBI) is becoming an increasing public health issue. With an annually
estimated 1.7 million TBIs in the United States (US) and nearly 70 million worldwide, the …

Dipeptidyl peptidase-4 (DPP-4) inhibitors are reported to exhibit promising effects on several
pathological processes associated with Parkinson's disease (PD). To explore its …