The advent of genome editing has transformed the therapeutic landscape for several
debilitating diseases, and the clinical outlook for gene therapeutics has never been more …

Although conventional chemotherapy has been successful to some extent, the main
drawbacks of chemotherapy are its poor bioavailability, high-dose requirements, adverse …

This Review is an overview of the unique characteristics of cyclodextrin in forming an
inclusion complex via host–guest noncovalent interactions. The modification of cyclodextrin …

A number of stimuli-responsive-based hydrogels has been widely explored in biomedical
applications in the last few decades because of their excellent biodegradability and …

The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Chemotherapy is currently one of the most effective ways to treat cancer. However,
traditional chemotherapy faces several obstacles to clinical trials, such as poor …

Over the past century, hydrogels have emerged as effective materials for an immense variety
of applications. The unique network structure of hydrogels enables very high levels of …

Two-dimensional metallacycles and three-dimensional metallacages constructed by
coordination-driven self-assembly have attracted much attention because they exhibit …

The development of supramolecular chemistry dates back to 1987 when Lehn, Cram, and
Pedersen won the Nobel Prize on account of their leading discoveries in the host–guest …

Adaptable hydrogels have recently emerged as a promising platform for three‐dimensional
(3D) cell encapsulation and culture. In conventional, covalently crosslinked hydrogels …