[HTML][HTML] Human induced pluripotent stem cell–derived liver-on-a-chip for studying drug metabolism: the challenge of the cytochrome P450 family

I Tamargo-Rubio, AB Simpson… - Frontiers in …, 2023 - frontiersin.org
The liver is the primary organ responsible for the detoxification and metabolism of drugs. To
date, a lack of preclinical models that accurately emulate drug metabolism by the human …

Exosomes derived from oviduct cells mediate the EGFR/MAPK signaling pathway in cumulus cells

SH Lee, HJ Oh, MJ Kim, BC Lee - Journal of Cellular …, 2020 - Wiley Online Library
Current studies indicate that application of oviduct cells (OCs) in in vitro system create
microenvironment similar to the in vivo conditions by releasing multiple growth factors which …

[HTML][HTML] Human adipose-derived stem cells' paracrine factors in conditioned medium can enhance porcine oocyte maturation and subsequent embryo development

SH Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
An essential requirement for the success of in vitro maturation (IVM) of the oocyte is to
provide an optimal microenvironment similar to in vivo conditions. Recently, somatic cell …

[HTML][HTML] IVM advances for early antral follicle-enclosed oocytes coupling reproductive tissue engineering to inductive influences of human chorionic gonadotropin and …

A Peserico, C Di Berardino, G Capacchietti… - International Journal of …, 2023 - mdpi.com
In vitro maturation (IVM) is not a routine assisted reproductive technology (ART) for oocytes
collected from early antral (EA) follicles, a large source of potentially available gametes …

[HTML][HTML] Effects of human endothelial progenitor cell and its conditioned medium on oocyte development and subsequent embryo development

SH Lee - International Journal of Molecular Sciences, 2020 - mdpi.com
Human endothelial progenitor cells (EPCs) secrete numerous growth factors, and they have
been applied to regenerative medicine for their roles in angiogenesis as well as …

Prenatal caffeine exposure caused H‐type blood vessel‐related long bone dysplasia via miR375/CTGF signaling

H He, H Luo, L Liu, Y Shangguan, X Xie… - The FASEB …, 2021 - Wiley Online Library
Caffeine has developmental toxicity. Prenatal caffeine exposure (PCE) caused intrauterine
growth retardation (IUGR) and multiple organ dysplasia. This study intended to explore the …

Clinical assessment of intravenous endothelial progenitor cell transplantation in dogs

SH Lee, JC Ra, HJ Oh, MJ Kim… - Cell …, 2019 - journals.sagepub.com
Endothelial progenitor cells (EPCs) have been applied for cell therapy because of their roles
in angiogenesis and neovascularization in ischemic tissue. However, adverse responses …

Co‐culturing or conditioned medium of Sertoli cells: Which one supports in vitro maturation of bovine oocytes and developmental competency of resulting embryos?

S Nazifi, H Nazari, H Hassanpour… - Veterinary Medicine …, 2022 - Wiley Online Library
Abstract Background Sertoli cells (SCs) as supportive cells in the seminiferous tubule play
an essential role in the nutrition and development of adjacent cells by secreting several …

The role of vasoactive, pro-, and antithrombogenic endothelial factors in the regulation of oocyte maturation in the treatment of infertility

VN Perfilova, EA Muzyko… - Obstetrics and …, 2023 - journals.eco-vector.com
Infertility is a global problem of the present-day world, whereas its incidence tends to
increase. To date, one of the most effective methods for infertility treatment is assisted …

[PDF][PDF] Effect of different oocyte retrieval and culture methods on in vitro maturation of bovine oocytes derived from vitrified ovarian tissue slices.

H Nazari, A Afzali, P Mirshokraei - 2023 - igbzpan.pl
In a successful method of ovarian tissue cryopreservation, there are always a number of
antral follicles remain intact, as a result of which the methods of retrieving and culturing …