[HTML][HTML] Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …
components across multiple spatial (from ion channel to organ) and temporal (from …
Computational modeling of the human atrial anatomy and electrophysiology
This review article gives a comprehensive survey of the progress made in computational
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
modeling of the human atria during the last 10 years. Modeling the anatomy has emerged …
Role of endo-epicardial dissociation of electrical activity and transmural conduction in the development of persistent atrial fibrillation
S Verheule, J Eckstein, D Linz, B Maesen… - Progress in biophysics …, 2014 - Elsevier
Atrial fibrillation (AF) is an arrhythmia that occurs as a result of numerous pathophysiological
processes in the atria. High rate, neurohumoral activation, aging and chronic stretch activate …
processes in the atria. High rate, neurohumoral activation, aging and chronic stretch activate …
euHeart: personalized and integrated cardiac care using patient-specific cardiovascular modelling
The loss of cardiac pump function accounts for a significant increase in both mortality and
morbidity in Western society, where there is currently a one in four lifetime risk, and costs …
morbidity in Western society, where there is currently a one in four lifetime risk, and costs …
Personalization of atrial anatomy and electrophysiology as a basis for clinical modeling of radio-frequency ablation of atrial fibrillation
Multiscale cardiac modeling has made great advances over the last decade. Highly detailed
atrial models were created and used for the investigation of initiation and perpetuation of …
atrial models were created and used for the investigation of initiation and perpetuation of …
Electrolyte disturbances differentially regulate sinoatrial node and pulmonary vein electrical activity: a contribution to hypokalemia-or hyponatremia-induced atrial …
YY Lu, CC Cheng, YC Chen, YK Lin, SA Chen… - Heart rhythm, 2016 - Elsevier
Background Hypokalemia and hyponatremia increase the occurrence of atrial fibrillation.
Sinoatrial nodes (SANs) and pulmonary veins (PVs) play a critical role in the …
Sinoatrial nodes (SANs) and pulmonary veins (PVs) play a critical role in the …
In-silico modeling of atrial repolarization in normal and atrial fibrillation remodeled state
MW Krueger, A Dorn, DUJ Keller, F Holmqvist… - Medical & biological …, 2013 - Springer
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and the total number of AF
patients is constantly increasing. The mechanisms leading to and sustaining AF are not …
patients is constantly increasing. The mechanisms leading to and sustaining AF are not …
Computational modeling of cardiac electrophysiology and arrhythmogenesis: toward clinical translation
The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …
components across multiple spatial (from ion channel to organ) and temporal (from …
How disruption of endo-epicardial electrical connections enhances endo-epicardial conduction during atrial fibrillation
Aims Loss of side-to-side electrical connections between atrial muscle bundles is thought to
underlie conduction disturbances predisposing to atrial fibrillation (AF). Putatively, disruption …
underlie conduction disturbances predisposing to atrial fibrillation (AF). Putatively, disruption …
Computational cardiology: how computer simulations could be used to develop new therapies and advance existing ones
This article reviews the latest developments in computational cardiology. It focuses on the
contribution of cardiac modelling to the development of new therapies as well as the …
contribution of cardiac modelling to the development of new therapies as well as the …