Obesity phenotypes, diabetes, and cardiovascular diseases

ME Piché, A Tchernof, JP Després - Circulation research, 2020 - Am Heart Assoc
This review addresses the interplay between obesity, type 2 diabetes mellitus, and
cardiovascular diseases. It is proposed that obesity, generally defined by an excess of body …

Visceral and ectopic fat, atherosclerosis, and cardiometabolic disease: a position statement

IJ Neeland, R Ross, JP Després… - The lancet Diabetes & …, 2019 - thelancet.com
Findings from epidemiological studies over the past 30 years have shown that visceral
adipose tissue, accurately measured by CT or MRI, is an independent risk marker of …

Cardiovascular and metabolic heterogeneity of obesity: clinical challenges and implications for management

IJ Neeland, P Poirier, JP Després - Circulation, 2018 - Am Heart Assoc
The prevalence of obesity has increased globally over the last 2 decades. Although the body
mass index has been a convenient and simple index of obesity at the population level …

Obesity subtypes, related biomarkers & heterogeneity

LPC Mayoral, GM Andrade, EPC Mayoral… - Indian Journal of …, 2020 - journals.lww.com
Obesity is a serious medical condition worldwide, which needs new approaches and
recognized international consensus in treating diseases leading to morbidity. The aim of this …

Precision nutrition: a review of personalized nutritional approaches for the prevention and management of metabolic syndrome

J de Toro-Martín, BJ Arsenault, JP Després, MC Vohl - Nutrients, 2017 - mdpi.com
The translation of the growing increase of findings emerging from basic nutritional science
into meaningful and clinically relevant dietary advices represents nowadays one of the main …

Pathophysiology of human visceral obesity: an update

A Tchernof, JP Després - Physiological reviews, 2013 - journals.physiology.org
Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Body fat distribution and risk of cardiovascular disease: an update

JP Després - Circulation, 2012 - Am Heart Assoc
Epidemiological, clinical, and mechanistic preclinical studies conducted in the field of
cardiovascular medicine have led to remarkable progress in our understanding of …

[HTML][HTML] Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective …

Emerging Risk Factors Collaboration - The Lancet, 2011 - thelancet.com
Background Guidelines differ about the value of assessment of adiposity measures for
cardiovascular disease risk prediction when information is available for other risk factors. We …

Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk

JP Després, I Lemieux, J Bergeron… - … , and vascular biology, 2008 - Am Heart Assoc
There is currently substantial confusion between the conceptual definition of the metabolic
syndrome and the clinical screening parameters and cut-off values proposed by various …

Fat depots, free fatty acids, and dyslipidemia

JO Ebbert, MD Jensen - Nutrients, 2013 - mdpi.com
Body fat deposition and excess free fatty acid (FFA) metabolism contribute to dyslipidemia
and the adverse health consequences of obesity. Individuals with upper body obesity have …