Mechanism and impact of heavy metal-aluminum (Al) toxicity on male reproduction: Therapeutic approaches with some phytochemicals

FEM Ali, KSA Badran, MA Baraka, HS Althagafy… - Life Sciences, 2024 - Elsevier
Heavy metals are ubiquitous environmental toxicants that have been known to have a
serious effect on human and animal health. Aluminum (Al) is a widely distributed metal in …

[HTML][HTML] Cognition, dopamine and bioactive lipids in schizophrenia

R Condray, JK Yao - Frontiers in bioscience (Scholar edition), 2011 - ncbi.nlm.nih.gov
Schizophrenia is a remarkably complex disorder with a multitude of behavioral and
biological perturbations. Cognitive deficits are a core feature of this disorder, and involve …

[HTML][HTML] Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors

AB Sonego, DS Prado, GT Vale… - Brain, behavior, and …, 2018 - Elsevier
The chronic use of drugs that reduce the dopaminergic neurotransmission can cause a
hyperkinetic movement disorder called tardive dyskinesia (TD). The pathophysiology of this …

Omega-3 fatty acids in first-episode schizophrenia-a randomized controlled study of efficacy and relapse prevention (OFFER): rationale, design, and methods

T Pawełczyk, M Grancow, M Kotlicka-Antczak… - BMC psychiatry, 2015 - Springer
Background Polyunsaturated fatty acid (PUFA) metabolism abnormalities have been long
implicated in the etiology of schizophrenia. Although several randomized clinical trials have …

Fatty acid status and its relationship to cognitive decline and homocysteine levels in the elderly

M Baierle, PH Vencato, L Oldenburg, S Bordignon… - Nutrients, 2014 - mdpi.com
Polyunsaturated fatty acids (PUFAs), especially the n-3 series, are known for their protective
effects. Considering that cardiovascular diseases are risk factors for dementia, which is …

Coenzyme Q10 and fish oil synergistically alleviate aluminum chloride-induced suppression of testicular steroidogenesis and antioxidant defense

NS Mohammad, MH Arafa, HH Atteia - Free radical research, 2015 - Taylor & Francis
Aluminum (Al) is an environmental xenobiotic that stimulates free radical generation and
hence reproductive toxicity. Coenzyme Q10 (CoQ10) effectively counteracts free radical …

Could dietary trans fatty acids induce movement disorders? Effects of exercise and its influence on Na+ K+-ATPase and catalase activity in rat striatum

AM Teixeira, VT Dias, CS Pase, K Roversi… - Behavioural brain …, 2012 - Elsevier
The influence of trans fatty acids (FA) on development of orofacial dyskinesia (OD) and
locomotor activity was evaluated. Rats were fed with diets enriched with 20% soybean oil …

Comparative study between two animal models of extrapyramidal movement disorders: prevention and reversion by pecan nut shell aqueous extract

F Trevizol, DM Benvegnú, RCS Barcelos… - Behavioural brain …, 2011 - Elsevier
Acute reserpine and subchronic haloperidol are animal models of extrapyramidal disorders
often used to study parkinsonism, akinesia and tardive dyskinesia. In humans, these usually …

Omega-3 decreases D1 and D2 receptors expression in the prefrontal cortex and prevents amphetamine-induced conditioned place preference in rats

VG Metz, HJ Segat, VT Dias, RCS Barcelos… - The Journal of …, 2019 - Elsevier
Amphetamine (AMPH) abuse is a serious public health problem due to the high addictive
potential of this drug, whose use is related to severe brain neurotoxicity and memory …

Oxidative stress and the antipsychotic-induced vacuous chewing movement model of tardive dyskinesia: evidence for antioxidant-based prevention strategies

J Lister, JN Nobrega, PJ Fletcher, G Remington - Psychopharmacology, 2014 - Springer
Rationale Despite decades of research, tardive dyskinesia (TD) remains a poorly
understood iatrogenic movement disorder with few effective treatments and no known cure …