Hydrazides are present in many bioactive molecules and exhibit a variety of biological
activities, such as insecticidal, herbicidal, antifungal, antitumor, and antiviral effects. In this …

Finding highly active molecular scaffold structures is always the key research content of new
pesticide discovery. In the research and development of new pesticides, the discovery of …

Ring rot induced by Botryosphaeria dothidea is a major cause of growth and postharvest
losses in various fruits. There is an urgent need to develop green fungicides due to pesticide …

The development of new green fungicides is an effective way to solve the resistance of
agricultural pathogens and plays an important role in promoting high-quality and …

To discover novel and effective antifungal candidates, a series of new curcumol derivatives
were designed, synthesized, and evaluated their antifungal activity against five …

Infectious diseases are a major concern around the world. Today, it is an urgent need for
new chemotherapeutics for infectious diseases. Because of that, our group designed …

In order to find compounds with novel structures and high antifungal activity, 26
phenylethanol derivatives containing a trifluoromethyl pyrazole pharmacophore were …

The increasing resistance problems of pathogens have drastically reduced the efficiency of
existing drugs and agricultural chemicals, increasing the difficulty of preventing and …

BACKGROUND Fungicides play a significant role in the integrated management of plant
pathogens. However, the irrational application of fungicides with similar structures has led to …

In screening for natural fungicidal leads, two series of novel 3-aryl-isoquinoline derivatives 8
and 9 were designed and synthesized based on sanguinarine, chelerythrine and berberine …