Ferrocifen type anti cancer drugs

G Jaouen, A Vessières, S Top - Chemical Society Reviews, 2015 - pubs.rsc.org
Despite current developments in therapeutics focusing on biotechnologically-oriented
species, the unflagging utility of small molecules or peptides in medicine is still producing …

Organometallic anticancer compounds

G Gasser, I Ott, N Metzler-Nolte - Journal of medicinal chemistry, 2011 - ACS Publications
The quest for alternative drugs to the well-known cisplatin and its derivatives, which are still
used in more than 50% of the treatment regimes for patients suffering from cancer, is highly …

Application of ferrocene and its derivatives in cancer research

C Ornelas - New Journal of Chemistry, 2011 - pubs.rsc.org
The use of ferrocene-based compounds for medicinal applications is an active research
area. Many reports have demonstrated that some ferrocenyl derivatives are highly active …

Ferrocene-based drugs, delivery nanomaterials and fenton mechanism: state of the art, recent developments and prospects

C Ornelas, D Astruc - Pharmaceutics, 2023 - mdpi.com
Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Designing organometallic compounds for catalysis and therapy

AL Noffke, A Habtemariam, AM Pizarro… - Chemical …, 2012 - pubs.rsc.org
Bioorganometallic chemistry is a rapidly developing area of research. In recent years
organometallic compounds have provided a rich platform for the design of effective catalysts …

A new age for iron: antitumoral ferrocenes

SS Braga, AMS Silva - Organometallics, 2013 - ACS Publications
From the core of the earth to the core of the archetypal organometallic compound ferrocene,
iron and its compounds contribute to create many aspects of our reality: the earth's …

Nanostructured materials functionalized with metal complexes: In search of alternatives for administering anticancer metallodrugs

WA Wani, S Prashar, S Shreaz… - Coordination chemistry …, 2016 - Elsevier
Nanotechnology has shown great promise in unraveling several important issues of
conventional anticancer chemotherapy. Expectations project that a new generation of …

Recent advances in the synthesis, biological activities and various applications of ferrocene derivatives

FA Larik, A Saeed, TA Fattah… - Applied …, 2017 - Wiley Online Library
Ferrocene derivatives constitute an important class of organometallic compounds with not
only an extensive range of biological activities but also diverse industrial as well as material …

Enhancing the activity of drugs by conjugation to organometallic fragments

P Chellan, PJ Sadler - Chemistry–A European Journal, 2020 - Wiley Online Library
Resistance to chemotherapy is a current clinical problem, especially in the treatment of
microbial infections and cancer. One strategy to overcome this is to make new derivatives of …

On the discovery, biological effects, and use of cisplatin and metallocenes in anticancer chemotherapy

S Gomez-Ruiz, D Maksimović-Ivanić… - Bioinorganic …, 2012 - Wiley Online Library
The purpose of this paper is to summarize mode of action of cisplatin on the tumor cells, a
brief outlook on the metallocene compounds as antitumor drugs as well as the future …