Lung cancer persists to contribute to one-quarter of cancer-associated deaths. Among the
different histologies, non-small cell lung cancer (NSCLC) alone accounts for 85% of the …

Evasion from apoptotic cell death is reported to be a pivotal mechanism by which tumor cells
acquire resistance to therapeutic treatment. Targeting the apoptotic pathways may constitute …

Background Non-small cell lung cancer (NSCLC) remains the most common cause of
cancer related death worldwide. Tumor-infiltrating macrophages are believed to play an …

Recent studies suggest that chemotherapy, in addition to its cytotoxic effects on tumor cells,
can induce a cascade of host events to support tumor growth and spread. Here, we used an …

We report detection of Baculoviral inhibitor of apoptosis repeat containing-5 (BIRC5) protein
biomarker in dog serum by label-free surface plasmon resonance (SPR) immunosensor …

Survivin is an inhibitor of apoptosis protein (IAP) family member preferentially expressed in a
myriad of clinical cancers. The complex functional mechanism and regulatory roles of …

Accumulating evidence suggests a role for inflammation in the development and
progression of cancer. Our group recently identified a cytokine gene signature in lung tissue …

Lilii Bulbus is a popular folk medicine in the worldwide and has attracted great attention due
to its bioactivity against respiratory system diseases (include lung cancers). This study was …

We previously identified a chemotherapy-induced paracrine inflammatory loop that
paradoxically mitigates the anti-tumor effect of chemotherapy and triggers metastatic …

Background Hyaluronan (HA) an important component of the extracellular matrix, has been
linked to tumor progression and drug resistance in several malignancies. However, limited …