Conspectus Coacervates are droplets formed by liquid–liquid phase separation (LLPS) and
are often used as model protocells–primitive cell-like compartments that could have aided …

The cytoplasm is densely packed with molecules that contribute to its nonideal behavior.
Cytosolic crowding influences chemical reaction rates, intracellular water mobility, and …

Biomolecular condensates form via processes that combine phase separation and
reversible associations of multivalent macromolecules. Condensates can be two-or …

Control of the electrochemical environment in living cells is typically attributed to ion
channels. Here, we show that the formation of biomolecular condensates can modulate the …

Biomolecular condensates are nonmembrane-bound assemblies of biological polymers
such as protein and nucleic acids. An increasingly accepted paradigm across the viral tree …

Cortical activity patterns are strongly modulated by fast synaptic inhibition mediated through
ionotropic, chloride-conducting receptors. Consequently, chloride homeostasis is ideally …

Biomolecular condensation is a key mechanism for organizing cellular processes in a
spatiotemporal manner. The phase-transition nature of this process defines a density …

Drought is one of the most serious abiotic stresses to land plants. Plants sense and respond
to drought stress to survive under water deficiency. Scientists have studied how plants sense …

Over the past decades, there has been a flourishing of phase-separated polymer gels.
Unlike traditional design methods that rely on chemical structure and polymer network …

We report the discovery that chemical reactions such as ATP hydrolysis can be catalyzed by
condensates formed by intrinsically disordered proteins (IDPs), which themselves lack any …