The neuroscience of drug reward and addiction

ND Volkow, M Michaelides, R Baler - Physiological reviews, 2019 - journals.physiology.org
Drug consumption is driven by a drug's pharmacological effects, which are experienced as
rewarding, and is influenced by genetic, developmental, and psychosocial factors that …

Obesity and addiction: neurobiological overlaps

ND Volkow, GJ Wang, D Tomasi, RD Baler - Obesity reviews, 2013 - Wiley Online Library
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …

Deficits in behavioural inhibition in substance abuse and addiction: a meta-analysis

JL Smith, RP Mattick, SD Jamadar… - Drug and alcohol …, 2014 - Elsevier
Aims Deficits in behavioural inhibitory control are attracting increasing attention as a factor
behind the development and maintenance of substance dependence. However, evidence …

Characterizing the cognitive effects of cocaine: a comprehensive review

DB Spronk, JHP van Wel, JG Ramaekers… - … & Biobehavioral Reviews, 2013 - Elsevier
Understanding the cognitive sequela of repeated cocaine use is a growing area of research
and is crucial to the development of cognitive models of addiction. We systematically …

Unbalanced neuronal circuits in addiction

ND Volkow, GJ Wang, D Tomasi, RD Baler - Current opinion in …, 2013 - Elsevier
Through sequential waves of drug-induced neurochemical stimulation, addiction co-opts the
brain's neuronal circuits that mediate reward, motivation to behavioral inflexibility and a …

Age and impulsive behavior in drug addiction: A review of past research and future directions

E Argyriou, M Um, C Carron, MA Cyders - Pharmacology Biochemistry and …, 2018 - Elsevier
Impulsive behavior is implicated in the initiation, maintenance, and relapse of drug-seeking
behaviors involved in drug addiction. Research shows that changes in impulsive behavior …

Impaired neural response to negative prediction errors in cocaine addiction

MA Parvaz, AB Konova, GH Proudfit… - Journal of …, 2015 - Soc Neuroscience
Learning can be guided by unexpected success or failure, signaled via dopaminergic
positive reward prediction error (+ RPE) and negative reward-prediction error (− RPE) …

Substance use initiation, particularly alcohol, in drug-naive adolescents: Possible predictors and consequences from a large cohort naturalistic study

I Ivanov, MA Parvaz, E Velthorst, RB Shaik… - Journal of the American …, 2021 - Elsevier
Objective It is unclear whether deviations in brain and behavioral development, which may
underpin elevated substance use during adolescence, are predispositions for or …

Blunted reward processing in remitted melancholic depression

A Weinberg, SA Shankman - Clinical Psychological Science, 2017 - journals.sagepub.com
Blunted reward response appears to be a trait-like marker of vulnerability for major
depressive disorder (MDD). As such, it should be present in remitted individuals; however …

Altered reward processing in pathological computer gamers–ERP‐results from a semi‐natural Gaming‐Design

ECP Duven, KW Müller, ME Beutel… - Brain and …, 2015 - Wiley Online Library
Abstract Introduction Internet Gaming Disorder has been added as a research diagnosis in
section III for the DSM‐V. Previous findings from neuroscientific research indicate an …