[HTML][HTML] Diabetic cardiomyopathy: current and future therapies. Beyond glycemic control

G Borghetti, D Von Lewinski, DM Eaton… - Frontiers in …, 2018 - frontiersin.org
Diabetes mellitus and the associated complications represent a global burden on human
health and economics. Cardiovascular diseases are the leading cause of death in diabetic …

Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways

K Huynh, BC Bernardo, JR McMullen… - Pharmacology & …, 2014 - Elsevier
Cardiovascular disease is the primary cause of morbidity and mortality among the diabetic
population. Both experimental and clinical evidence suggest that diabetic subjects are …

[HTML][HTML] Coenzyme Q10 Supplementation for the Reduction of Oxidative Stress: Clinical Implications in the Treatment of Chronic Diseases

FM Gutierrez-Mariscal, AP Arenas-de Larriva… - International journal of …, 2020 - mdpi.com
Apart from its main function in the mitochondria as a key element in electron transport,
Coenzyme Q10 (CoQ10) has been described as having multiple functions, such as oxidant …

Role of oxidative modifications in atherosclerosis

R Stocker, JF Keaney Jr - Physiological reviews, 2004 - journals.physiology.org
This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

[HTML][HTML] Oxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice

JS Johansen, AK Harris, DJ Rychly, A Ergul - Cardiovascular diabetology, 2005 - Springer
Cardiovascular complications, characterized by endothelial dysfunction and accelerated
atherosclerosis, are the leading cause of morbidity and mortality associated with diabetes …

[HTML][HTML] Metabolism and function of coenzyme Q

M Turunen, J Olsson, G Dallner - Biochimica et Biophysica Acta (BBA) …, 2004 - Elsevier
Coenzyme Q (CoQ) is present in all cells and membranes and in addition to be a member of
the mitochondrial respiratory chain it has also several other functions of great importance for …

Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics

HN Bhagavan, RK Chopra - Free radical research, 2006 - Taylor & Francis
Available data on the absorption, metabolism and pharmacokinetics of coenzyme Q10
(CoQ10) are reviewed in this paper. CoQ10 has a fundamental role in cellular bioenergetics …

Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome

A Kumar, H Kaur, P Devi, V Mohan - Pharmacology & therapeutics, 2009 - Elsevier
Coenzyme Q10 (ubiquinone) is a mitochondrial coenzyme which is essential for the
production of ATP. Being at the core of cellular energy processes it assumes importance in …

Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials

RS Birjmohun, BA Hutten, JJP Kastelein… - Journal of the American …, 2005 - jacc.org
Objectives: The aim of this research was to estimate the efficacy and safety of current high-
density lipoprotein cholesterol (HDL-C)-increasing drugs. Background: Epidemiologic …

Endothelial dysfunction in diabetes: from mechanisms to therapeutic targets

MA Potenza, S Gagliardi, C Nacci… - Current medicinal …, 2009 - ingentaconnect.com
Micro-and macrovascular complications are major causes of disability and death in patients
with diabetes mellitus. Functional impairment of endothelial activity precedes the …