Gut–skin axis: current knowledge of the interrelationship between microbial dysbiosis and skin conditions
B De Pessemier, L Grine, M Debaere, A Maes… - Microorganisms, 2021 - mdpi.com
The microbiome plays an important role in a wide variety of skin disorders. Not only is the
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …
skin microbiome altered, but also surprisingly many skin diseases are accompanied by an …
[HTML][HTML] Mouse models of psoriasis: a comprehensive review
The use of preclinical animal models of psoriasis has significantly increased over the last
three decades, with each model having unique strengths and limitations. Some models …
three decades, with each model having unique strengths and limitations. Some models …
Updated perspectives on keratinocytes and psoriasis: keratinocytes are more than innocent bystanders
LI Ortiz-Lopez, V Choudhary… - Psoriasis: Targets and …, 2022 - Taylor & Francis
Psoriasis is a complex disease triggered by genetic, immunologic, and environmental
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …
stimuli. Many genes have been linked to psoriasis, like the psoriasis susceptibility genes …
TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy
RK Gupta, DT Gracias, DS Figueroa, H Miki… - Science …, 2021 - science.org
TNF and IL-17 are two cytokines that drive dysregulated keratinocyte activity, and their
targeting is highly efficacious in patients with psoriasis, but whether these molecules act with …
targeting is highly efficacious in patients with psoriasis, but whether these molecules act with …
[HTML][HTML] The snowballing literature on imiquimod-induced skin inflammation in mice: a critical appraisal
Since 2009, the imiquimod-or Aldara-induced (3M Pharmaceuticals, St. Paul, MN) model of
acute skin inflammation has become the most widely used mouse model in preclinical …
acute skin inflammation has become the most widely used mouse model in preclinical …
[HTML][HTML] Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development
Psoriasis has long been associated with inflammatory bowel disease (IBD); however, a
causal link is yet to be established. Here, we demonstrate that imiquimod-induced psoriasis …
causal link is yet to be established. Here, we demonstrate that imiquimod-induced psoriasis …
Murine models of psoriasis and their usefulness for drug discovery
SY Chuang, CH Lin, CT Sung… - Expert opinion on drug …, 2018 - Taylor & Francis
Introduction: Psoriasis is an autoimmune skin disease characterized by red plaques with
silver or white multilayered scales with a thickened acanthotic epidermis. Using mouse …
silver or white multilayered scales with a thickened acanthotic epidermis. Using mouse …
[HTML][HTML] Research techniques made simple: murine models of human psoriasis
Psoriasis vulgaris is a common, inflammatory skin disease affecting approximately 3% of the
population in the United States. The etiology of psoriasis and its associated comorbidities …
population in the United States. The etiology of psoriasis and its associated comorbidities …
Antipsoriatic effects of Wannachawee recipe on Imiquimod‐induced psoriasis‐like dermatitis in BALB/c mice
M Na Takuathung, A Wongnoppavich… - Evidence‐Based …, 2018 - Wiley Online Library
Psoriasis is a common immune‐mediated chronic inflammatory skin disease characterized
by thick and erythema raised plaques with adherent silvery scales. T‐cells are activated via …
by thick and erythema raised plaques with adherent silvery scales. T‐cells are activated via …
Rapamycin alleviates 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin-Induced aggravated dermatitis in mice with imiquimod-induced psoriasis-like dermatitis by inducing …
HR Kim, JC Kim, SY Kang, HO Kim, CW Park… - International Journal of …, 2021 - mdpi.com
Recently, the mTOR signaling has emerged as an important player in the pathogenesis of
psoriasis. We previously found that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-induced …
psoriasis. We previously found that 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD)-induced …