Multidrug resistance in cancer is linked to expression of the P-glycoprotein multidrug
transporter (Pgp, ABCB1), which exports many structurally diverse compounds from cells …

Cellular membranes exhibit a fascinating variety of different morphologies, which are
continuously remodeled by transformations of membrane shape and topology. This …

Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains
unclear. Here, we show that FAs trigger caveolae-dependent CD36 internalization, which in …

Late endosomes (LEs) have characteristic intracellular distributions determined by their
interactions with various motor proteins. Motor proteins associated to the dynactin subunit …

Controlled distribution of lipids across various cell membranes is crucial for cell homeostasis
and regulation. We developed an imaging method that allows simultaneous in situ …

Our aim was to examine the effects of seven high-intensity aerobic interval training (HIIT)
sessions over 2 wk on skeletal muscle fuel content, mitochondrial enzyme activities, fatty …

The transfer of cholesterol from the outer to the inner mitochondrial membrane is the rate-
limiting step in hormone-induced steroid formation. To ensure that this step is achieved …

Recent research has provided an abundance of new information on membrane
biochemistry. Now more than ever, it is essential to update our current understanding of …

In contrast to ordinary condensed matter systems,“living systems” are unique. They are
based on molecular compartments that reproduce themselves through (i) an uptake of …

Fatty acid bioavailability can be managed through the physicochemical properties of lipid
such as lipid-droplet size, lipiddroplet ultrastructure (lipids organization between core and …