• An overview of the current understanding of bleeding and thrombosis in cirrhosis.• An
evidence-based justification for bleeding risk assessment in patients with cirrhosis before …

Description This expert review was commissioned and approved by the AGA Institute
Clinical Practice Updates Committee and the AGA Governing Board to provide timely …

Disorders of the mesenteric, portal, and hepatic veins and mesenteric and hepatic arteries
have important clinical consequences and may lead to acute liver failure, chronic liver …

The aims of severe perioperative bleeding management are three-fold. First, preoperative
identification by anamesis and laboratory testing of those patients for whom the …

Background & Aims Patients with thrombocytopenia and chronic liver disease (CLD) may
require platelet transfusions before scheduled procedures to decrease risk of bleeding. We …

Patients with acute and chronic liver disease frequently acquire unique changes in
haemodynamic and haemostatic pathways that may result in life-threatening bleeding and …

Background Eltrombopag is an oral thrombopoietin-receptor agonist. This study evaluated
the efficacy of eltrombopag for increasing platelet counts and reducing the need for platelet …

Thrombocytopenia may be associated with increased bleeding risk impacting timing and
outcome of invasive procedures in patients with chronic liver disease (CLD) …

BACKGROUND & AIMS: Patients with acute liver injury/failure (ALI/ALF) are assumed to
have a bleeding diathesis on the basis of elevated INR; however, clinically significant …

Liver disease results in complex alterations of all 3 phases of hemostasis. It is now
recognized that hemostasis is rebalanced in chronic liver disease. The fall in clotting factor …