Recent work has shed light on the abundance and diversity of d-amino acids in bacterial
extracellular/periplasmic molecules, bacterial cell culture, and bacteria-rich environments …

Some development stages of the trypanosomatid protozoan parasites are well adapted to in
vitro culture. They can be maintained in rich medium containing large excess of glucose and …

Chagas disease is a chronic systemic infection transmitted by Trypanosoma cruzi. Its life
cycle consists of different stages in vector insects and host mammals. Trypanosoma cruzi …

Kinetoplastids, including the human pathogens Trypanosoma brucei, Trypanosoma cruzi
and Leishmania, are the only known organisms that do not regulate the transcription of …

Trypanosoma brucei, as well as Trypanosoma cruzi and more than 20 species of the genus
Leishmania, form a group of flagellated protists that threaten human health. These …

Amino acids are among the most important molecules in nature since they play central roles
both as building blocks of proteins and as intermediates in metabolism. The amino acid …

Microbes have evolved a diverse range of strategies to subvert the host immune system. The
protozoan parasite Trypanosoma cruzi, the causative agent of Chagas disease, provides a …

Using as the host cell, a proline‐requiring mutant of Chinese hamster ovary cell (CHO‐K1), it
was possible to arrest the differentiation of amastigote forms of Trypanosoma cruzi at the …

The aim of this review is to gather the current knowledge of Trypanosoma cruzi's virulence
factors described to date in an integrative way, relating these with the parasite's life cycle …

Amino acid racemases catalyze the stereoinversion of the chiral Cα to produce the d-
enantiomers that participate in biological processes, such as cell wall construction in …