[HTML][HTML] The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics
PMR Cruz, H Mo, WJ McConathy, N Sabnis… - Frontiers in …, 2013 - frontiersin.org
While the unique metabolic activities of malignant tissues as potential targets for cancer
therapeutics has been the subject of several recent reviews, the role of cholesterol …
therapeutics has been the subject of several recent reviews, the role of cholesterol …
[HTML][HTML] The potential of isoprenoids in adjuvant cancer therapy to reduce adverse effects of statins
The mevalonate pathway provides sterols for membrane structure and nonsterol
intermediates for the post-translational modification and membrane anchorage of growth …
intermediates for the post-translational modification and membrane anchorage of growth …
Potential of tocotrienols in the prevention and therapy of Alzheimer's disease
Currently there is no cure for Alzheimer's disease (AD); clinical trials are underway to reduce
amyloid generation and deposition, a neuropathological hallmark in brains of AD patients …
amyloid generation and deposition, a neuropathological hallmark in brains of AD patients …
[HTML][HTML] Crocetin and crocin decreased cholesterol and triglyceride content of both breast cancer tumors and cell lines
SA Hashemi, SZ Bathaie… - Avicenna Journal of …, 2020 - ncbi.nlm.nih.gov
Objective: Inhibition of lipid metabolism in breast cancer has been suggested as an effective
approach for cancer therapy. Saffron-derived crocetin (Crt) and crocin (Cro) with the known …
approach for cancer therapy. Saffron-derived crocetin (Crt) and crocin (Cro) with the known …
Synergistic Impact of d-δ-Tocotrienol and Geranylgeraniol on the Growth and HMG CoA Reductase of Human DU145 Prostate Carcinoma Cells
H Yeganehjoo, R DeBose-Boyd, BK McFarlin… - Nutrition and …, 2017 - Taylor & Francis
The growth-suppressive effect of d-δ-tocotrienol and geranylgeraniol is at least partially
attributed to their impact on 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase …
attributed to their impact on 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase …
Synergistic Impact of Xanthorrhizol and d-δ-Tocotrienol on the Proliferation of Murine B16 Melanoma Cells and Human DU145 Prostate Carcinoma Cells
D Chan, ML Meister, CR Madhani, M Elfakhani… - Nutrition and …, 2021 - Taylor & Francis
Isoprenoids suppress the mevalonate pathway that provides prenyl groups for the
posttranslational modification of growth-regulating proteins. We hypothesize that …
posttranslational modification of growth-regulating proteins. We hypothesize that …
Benzamide or benzamine compounds useful as anticancer agents for the treatment of human cancers
J DeBrabander, L Parada - US Patent 10,112,948, 2018 - Google Patents
2016-06-30 Assigned to THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS
SYSTEM reassignment THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS …
SYSTEM reassignment THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS …
Targeting emopamil binding protein (EBP) with small molecules that induce an abnormal feedback response by lowering endogenous cholesterol biosynthesis
J De Brabander, JW Shay, W Wang… - US Patent …, 2018 - Google Patents
2016-07-08 Assigned to BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
reassignment BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM …
reassignment BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM …
Therapeutics targeting truncated adenomatous polyposis coli (APC) proteins
J DeBrabander, JW Shay, W Wang - US Patent 10,577,344, 2020 - Google Patents
2019-04-12 Assigned to THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS
SYSTEM reassignment THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS …
SYSTEM reassignment THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS …
Compositions of xanthorrhizol and tocochromanol (tocotrienol), and methods of use
DHY Chan, CR Madhani, M Elfakhani… - US Patent …, 2021 - Google Patents
(57) ABSTRACT A dietary supplement composition provided synergistic effects of
xanthorrhizol and tocotrienol on malignancies. A blend of xanthorrhizol and delta tocotrienol …
xanthorrhizol and tocotrienol on malignancies. A blend of xanthorrhizol and delta tocotrienol …