Recent advances in chemistry and therapeutic potential of functionalized quinoline motifs–a review

OO Ajani, KT Iyaye, OT Ademosun - RSC advances, 2022 - pubs.rsc.org
Quinoline, which consists of benzene fused with N-heterocyclic pyridine, has received
considerable attention as a core template in drug design because of its broad spectrum of …

Plant allelochemicals as sources of insecticides

I Tlak Gajger, SA Dar - Insects, 2021 - mdpi.com
Simple Summary Due to the banning of many synthetic pesticides, current intensive farming
systems require us to develop new approaches to integrated pest management. Devastating …

Anticancer, antioxidant, antiviral and antimicrobial activities of Kei Apple (Dovyalis caffra) fruit

H Qanash, R Yahya, MM Bakri, AS Bazaid… - Scientific Reports, 2022 - nature.com
Secondary plant metabolites remain one of the key sources of therapeutic agents despite
the development of new approaches for the discovery of medicinal drugs. In the current …

Alkaloids as potential antivirals. A comprehensive review

S Faisal, SL Badshah, B Kubra, AH Emwas… - Natural Products and …, 2023 - Springer
Alkaloids are a diverse group of natural phytochemicals. These phytochemicals in plants
provide them protection against pests, and herbivorous organisms and also control their …

Genus Sophora: a comprehensive review on secondary chemical metabolites and their biological aspects from past achievements to future perspectives

HI Abd-Alla, D Souguir, MO Radwan - Archives of pharmacal research, 2021 - Springer
Sophora is deemed as one of the most remarkable genera of Fabaceae, and the third
largest family of flowering plants. The genus Sophora comprises approximately 52 species …

[HTML][HTML] Rational drug design, synthesis, and biological evaluation of novel N-(2-arylaminophenyl)-2, 3-diphenylquinoxaline-6-sulfonamides as potential antimalarial …

AH Shntaif, S Khan, G Tapadiya, A Chettupalli… - Digital Chinese …, 2021 - Elsevier
Objective Sulfanilamide, sulfadiazine, and dapsone were the first sulfonamides to be used to
treat malaria by disrupting the folate biosynthesis process, which is essential for parasite …

Toxin degradation by rumen microorganisms: a review

ZH Loh, D Ouwerkerk, AV Klieve, NL Hungerford… - Toxins, 2020 - mdpi.com
Animal feeds may contain exogenous compounds that can induce toxicity when ruminants
ingest them. These toxins are secondary metabolites originating from various sources …

Role of secondary metabolites in distressed microalgae

M Kolackova, A Janova, M Dobesova, M Zvalova… - Environmental …, 2023 - Elsevier
Proficient photosynthetic microalgae/cyanobacteria produce a remarkable amount of various
biomolecules. Secondary metabolites (SM) represent high value products for global biotrend …

The use of antimalarial plants as traditional treatment in Papua Island, Indonesia

M Budiarti, A Maruzy, R Mujahid, AN Sari… - Heliyon, 2020 - cell.com
Abstracts The residents of the Eastern part of Indonesia, specifically, Papua and West Papua
provinces, are dependent on traditional medicines with the use of plants, which includes …

Synthesis, in-vitro biological evaluation, and molecular docking study of novel spiro-β-lactam-isatin hybrids

A Jarrahpour, Z Jowkar, Z Haghighijoo… - Medicinal Chemistry …, 2022 - Springer
In our ongoing search for bioactive compounds, a class of novel spiro-β-lactam isatin
hybrids has been synthesized through a [2+ 2] cycloaddition reaction from 1-allyl-3 …