A meta-analysis of pro-inflammatory cytokines in autism spectrum disorders: Effects of age, gender, and latitude

A Saghazadeh, B Ataeinia, K Keynejad… - Journal of psychiatric …, 2019 - Elsevier
Background Autism spectrum disorders (ASD) occur in 1.5% of the general population
worldwide. Studies suggest that ASD might have more costs than diabetes and attention …

Systematic review and meta-analysis: pharmacological and nonpharmacological interventions for persistent nonepisodic irritability

R Breaux, R Baweja, HM Eadeh, DM Shroff… - Journal of the American …, 2023 - Elsevier
Objective This meta-analysis examined the efficacy of available pharmacological and
nonpharmacological interventions for irritability among youth with autism spectrum disorder …

Impact of antipsychotics in children and adolescents with autism spectrum disorder: a systematic review and meta-analysis

GL D'Alò, F De Crescenzo, L Amato, F Cruciani… - Health and quality of life …, 2021 - Springer
Background The net health benefit of using antipsychotics in children and adolescents with
ASD is unclear. This review was performed to provide the evidence necessary to inform the …

[HTML][HTML] A white paper on a neurodevelopmental framework for drug discovery in autism and other neurodevelopmental disorders

CM Diaz-Caneja, MW State, RJ Hagerman… - European …, 2021 - Elsevier
In the last decade there has been a revolution in terms of genetic findings in
neurodevelopmental disorders (NDDs), with many discoveries critical for understanding …

Update on statin treatment in patients with neuropsychiatric disorders

R Avan, A Sahebnasagh, J Hashemi, M Monajati… - Life, 2021 - mdpi.com
Statins are widely accepted as first-choice agents for the prevention of lipid-related
cardiovascular diseases. These drugs have both anti-inflammatory and anti-oxidant …

Emerging drugs for the treatment of irritability associated with autism spectrum disorder

A Shamabadi, H Karimi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Autism spectrum disorder (ASD) is an early-onset disorder with a prevalence of
1% among children and reported disability-adjusted life years of 4.31 million. Irritability is a …

Prednisolone as adjunctive treatment to risperidone in children with regressive type of autism spectrum disorder: a randomized, placebo-controlled trial

M Malek, A Ashraf-Ganjouei, K Moradi… - Clinical …, 2020 - journals.lww.com
Objectives This study aimed to evaluate efficacy and safety of prednisolone as an adjunctive
treatment to risperidone, in children with regressive autism spectrum disorder (ASD) …

Vortioxetine as adjunctive therapy to risperidone for treatment of patients with chronic schizophrenia: A randomised, double-blind, placebo-controlled clinical trial

E Moazen-Zadeh, S Bayanati, K Ziafat… - Journal of …, 2020 - journals.sagepub.com
Introduction and objectives: Vortioxetine, a novel antidepressant, may be an interesting
candidate for adjunctive therapy of schizophrenia. Our primary objective was to investigate …

Palmitoylethanolamide as adjunctive therapy for autism: Efficacy and safety results from a randomized controlled trial

M Khalaj, A Saghazadeh, E Shirazi… - Journal of psychiatric …, 2018 - Elsevier
Inflammation as well as glutamate excitotoxicity have been proposed to participate in the
propagation of autism. Palmitoylethanolamide (PEA) is an endocannabinoid proven to …

l-Carnosine As an Adjunctive Therapy to Risperidone in Children with Autistic Disorder: A Randomized, Double-Blind, Placebo-Controlled Trial

R Hajizadeh-Zaker, A Ghajar… - Journal of child and …, 2018 - liebertpub.com
Objectives: This study aimed at investigating the efficacy and tolerability of l-carnosine as an
add-on to risperidone in the management of children with autism. Methods: This was a 10 …