Heme oxygenase catalyzes the rate-limiting step in heme degradation in order to generate
biliverdin, carbon monoxide (CO), and iron. The inducible form of the enzyme, heme …

The heme oxygenase-1 (HO-1) enzyme system remains an attractive therapeutic target for
the treatment of inflammatory conditions. HO-1, a cellular stress protein, serves a vital …

Turmeric, derived from the plant Curcuma longa, is a gold-colored spice commonly used in
the Indian subcontinent, not only for health care but also for the preservation of food and as …

The heme oxygenases, which consist of constitutive and inducible isozymes (HO-1, HO-2),
catalyze the rate-limiting step in the metabolic conversion of heme to the bile pigments (ie …

The neuroprotective role of phenolic acids from food has previously been reported by many
authors. In this review, the role of phenolic acids in ameliorating depression …

Covering: 2000 to 2013 Oxidative stress is the central component of chronic diseases. The
nuclear factor erythroid 2-related factor 2/antioxidant response element (Nrf2/ARE) pathway …

This review is intended to stimulate interest in the effect of increased expression of heme
oxygenase-1 (HO-1) protein and increased levels of HO activity on normal and pathological …

Although oxidants clearly possess the capacity to behave in a random and destructive
fashion, growing evidence suggests that in many instances the production of reactive …

Over the last decade, studies have unraveled many aspects of endogenous production and
physiological functions of carbon monoxide (CO). The majority of endogenous CO is …

The transcription factor Nrf2, which normally exists in an inactive state as a consequence of
binding to a cytoskeleton-associated protein Keap1, can be activated by redox-dependent …