Identification of potent inhibitors of HDAC2 from herbal products for the treatment of colon cancer: Molecular docking, molecular dynamics simulation, MM/GBSA …

M Khanal, A Acharya, R Maharjan, K Gyawali… - Plos one, 2024 - journals.plos.org
The histone deacetylase 2 (HDAC2), an enzyme involved in gene regulation, is a potent
drug target for the treatment of colon cancer. Phytocompounds having anticancer properties …

Computational DFT analysis and molecular modeling on imidazole derivatives used as corrosion inhibitors for aluminum in acidic media

S Bousba, H Allal, M Damous, S Maza - Computational and Theoretical …, 2023 - Elsevier
The corrosion inhibiting effect of imidazole derivatives on aluminum was studied using
density functional theory (DFT) calculations to assess the relationship between molecular …

[HTML][HTML] Evaluating the in vitro antidiabetic, antibacterial and antioxidant properties of copper (II) Schiff base complexes: An experimental and computational studies

TL Yusuf, I Waziri, KA Olofinsan, EO Akintemi… - Journal of Molecular …, 2023 - Elsevier
In recent years, metal-based compounds have been explored as potential remedies for
major health issues such as diabetes, bacterial infections, and oxidative stress, which impact …

Photodegradation of bisphenol A by ZnS combined with H2O2: Evaluation of photocatalytic activity, reaction parameters, and DFT calculations

MMP Barros, KJC Almeida, MVS Conceição… - Journal of Molecular …, 2023 - Elsevier
Bisphenol A (BFA) is a synthetic emergent contaminant with wide industrial applications and
resistant to degradation by conventional treatment methods, which makes the use of …

The effect of structural configuration on the DNA binding and in vitro antioxidant properties of new copper (ii) N 2 O 2 Schiff base complexes

TL Yusuf, DC Akintayo, SD Oladipo… - New Journal of …, 2022 - pubs.rsc.org
The interaction of transition metal complexes with DNA and plasma protein gives insight into
the development of new materials for medical and biotechnology applications. Thus, we …

Synthesis, in-vitro and in-silico antibacterial and computational studies of selected thiosemicarbazone-benzaldehyde derivatives as potential antibiotics

AA Olanrewaju, DG Oke, DO Adekunle, OA Adeleke… - SN Applied …, 2023 - Springer
Three new Schiff bases,(Z)-2-(4-(dimethylamino) benzylidene)-N-
methylhydrazinecarbothioamide (PDM),(Z)-2-(2-hydroxy-5-nitrobenzylidene)-N …

Cheminformatics bioprospection of selected medicinal plants metabolites against trypsin cleaved VP4 (spike protein) of rotavirus A

AA Lanrewaju, AM Enitan-Folami… - Journal of …, 2024 - Taylor & Francis
Rotaviruses have continued to be the primary cause of acute dehydrating diarrhoea in
children under five years of age despite the global introduction of four World Health …

Waste to Medicine: Evidence from Computational Studies on the Modulatory Role of Corn Silk on the Therapeutic Targets Implicated in Type 2 Diabetes Mellitus

A Akoonjee, AA Lanrewaju, FO Balogun, NP Makunga… - Biology, 2023 - mdpi.com
Simple Summary Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance
and/or defective insulin production in the human body. Corn silk (CS), an abundant, readily …

Investigating the effects of solvent polarity and temperature on the molecular, photophysical, and thermodynamic properties of sinapic acid using DFT and TDDFT

U Sherefedin, A Belay, K Gudishe, A Kebede… - RSC …, 2024 - pubs.rsc.org
Sinapic acid (SA) is widely used in cosmetics, foods, and pharmaceuticals due to its
antioxidant, anti-inflammatory, neuroprotective, antimicrobial, antifungal, anticancer, and …

Indole derivatives as organic corrosion inhibitors of low carbon steel in HCl medium-experimental and theoretical approach

FK Ojo, IA Adejoro, JA Lori, OE Oyeneyin, KG Akpomie - Chemistry Africa, 2022 - Springer
Corrosion remains a major problem in the manufacturing industries and the whole world at
large, hence the need to control it. Organic molecules have been used in the past and recent …