[HTML][HTML] Plants-based medicine implication in the evolution of chronic liver diseases

M Foghis, SG Bungau, AF Bungau, CM Vesa… - Biomedicine & …, 2023 - Elsevier
Hepatic disorders are considered major health problems, due to their high incidence,
increased risk of chronicling or death and the costs involved in therapies. A large number of …

Paraoxonases: metabolic role and pharmacological projection

C Moya, S Máñez - Naunyn-Schmiedeberg's archives of pharmacology, 2018 - Springer
Atherosclerosis is one of the leading causes of death in Western countries, with high-density
lipoproteins (HDL) playing an important protective role due to their ability to inhibit oxidation …

Discovery of potential mTOR inhibitors from Cichorium intybus to find new candidate drugs targeting the pathological protein related to the breast cancer: an …

HO Rasul, BK Aziz, DD Ghafour, A Kivrak - Molecular Diversity, 2023 - Springer
Breast cancer is the most common malignancy among women. It is a complex condition with
many subtypes based on the hormone receptor. The mammalian target of the rapamycin …

The Anti-Inflammatory and Antioxidant Effects of Salvia officinalis on Lipopolysaccharide-Induced Inflammation in Rats

UK Kolac, MC Ustuner, N Tekin, D Ustuner… - Journal of medicinal …, 2017 - liebertpub.com
Salvia officinalis, which has a high phenolic acid and flavonoid content, is a powerful
antioxidant and anti-inflammatory herb. Inflammation plays an important role in the …

Comparative analysis of the protective effects of curcumin and N-acetyl cysteine against paracetamol-induced hepatic, renal, and testicular toxicity in Wistar rats

ZK El-Maddawy, YS El-Sayed - Environmental science and pollution …, 2018 - Springer
This study aimed to investigate the possible protective role of curcumin (CUR) vs. N-acetyl
cysteine (NAC) against paracetamol (PCM)-induced oxidative damage and impairment of …

Prebiotic supplementation modulates advanced glycation end-products (AGEs), soluble receptor for AGEs (sRAGE), and cardiometabolic risk factors through …

MA Farhangi, P Dehghan, N Namazi - European journal of nutrition, 2020 - Springer
Purpose The oxidative stress plays a key role in the initiation, propagation, and development
of the complications of type 2 diabetes mellitus (T2DM). This trial aimed to evaluate the …

Synergistic ameliorative effects of sesame oil and alpha-lipoic acid against subacute diazinon toxicity in rats: hematological, biochemical, and antioxidant studies

MM Abdel-Daim, R Taha, EW Ghazy… - Canadian journal of …, 2016 - cdnsciencepub.com
Diazinon (DZN) is a common organophosphorus insecticide extensively used for agriculture
and veterinary purposes. DZN toxicity is not limited to insects; it also induces harmful effects …

Hepato-protective effect of rutin via IL-6/STAT3 pathway in CCl4-induced hepatotoxicity in rats

MM Hafez, NO Al-Harbi, AR Al-Hoshani… - Biological research, 2015 - Springer
Abstract Background Carbon tetrachloride (CCl 4) induces hepatotoxicity in animal models,
including the increased blood flow and cytokine accumulation that are characteristic of …

Chicoric acid ameliorates lipopolysaccharide-induced oxidative stress via promoting the Keap1/Nrf2 transcriptional signaling pathway in BV-2 microglial cells and …

Q Liu, Y Hu, Y Cao, G Song, Z Liu… - Journal of agricultural and …, 2017 - ACS Publications
As a major nutraceutical component of a typical Mediterranean vegetable chicory, chicoric
acid (CA) has been well-documented due to its excellent antioxidant and antiobesity …

The hepatocurative effects of Cynara scolymus L. leaf extract on carbon tetrachloride-induced oxidative stress and hepatic injury in rats

E Colak, MC Ustuner, N Tekin, E Colak, D Burukoglu… - SpringerPlus, 2016 - Springer
Cynara scolymus is a pharmacologically important medicinal plant containing phenolic
acids and flavonoids. Experimental studies indicate antioxidant and hepatoprotective effects …