Alcohols and their derivatives are ubiquitous and versatile motifs in organic synthesis.
Deoxygenative transformations of these compounds are often challenging due to the …

With their highly reactive respective C− Na and N− Na bonds, organosodium and sodium
amide reagents could be viewed as obvious replacements or even superior reagents to the …

Deaggregating the alkyl sodium NaCH2SiMe3 with polydentate nitrogen ligands enables
the preparation and characterisation of new, hydrocarbon soluble chelated alkylsodium …

Polar reactive organometallic species have been key reagents in synthesis for more than a
century. Stereodefined 1, 2-dimetallated alkenes offer promising synthetic utility; however …

Advancing the development of perfecting the use of polar organometallics in bio‐inspired
solvents, we report on the effective generation in batch of organosodium compounds, by the …

The solvent-dependent reactivity of sodium hexamethyldisilazide (NaHMDS) toward carbon-
centered electrophiles reveals reactions that are poorly represented or unrepresented in the …

Abstract Though LiTMP (TMP= 2, 2′, 6, 6′‐tetramethylpiperidide) is a commonly used
amide, surprisingly the heavier NaTMP has hardly been utilised. Here, by mixing NaTMP …

Profiting from the dual high basicity and nucleophilicity of organosodium complexes, here
we report the stepwise lateral metalation of a wide range of alkyl arenes (MeAr), mediated …

The preparation of sodium isopropyl (trimethylsilyl) amide (NaPTA), sodium (1-phenylethyl)(
trimethylsilyl) amide (NaPETA), sodium tert-butyl (trimethylsilyl) amide (NaBTA), and …

Organolithium compounds represent one of the most widely utilised commodity reagents in
synthetic chemistry. However, their analogues with the heavier alkali‐metal sodium are …