Tethered cord syndrome from pediatric and adult perspectives: a comprehensive systematic review of 6135 cases

K He, K Wang, Z Liu, L Zhang, S Liu, X Zhang… - Neurosurgical …, 2024 - thejns.org
OBJECTIVE This study aimed to investigate the differences in clinical features, diagnostic
examination, treatment, and pathological results between adult-onset and pediatric-onset …

Filum terminale: a comprehensive review with anatomical, pathological, and surgical considerations

Q Jiang, B Tao, G Gao, M Sun, H Wang, J Li, Z Wang… - World Neurosurgery, 2022 - Elsevier
The conus medullaris is the distal tapering end of the spinal cord, and the filum terminale
(FT) is regarded as a bundle of nonfunctional fibrous tissue; therefore, some scholars call it …

[HTML][HTML] Not just an anchor: the human filum terminale contains stretch sensitive and nociceptive nerve endings and responds to electrical stimulation with paraspinal …

PM Klinge, A McElroy, OP Leary, JE Donahue… - …, 2022 - journals.lww.com
BACKGROUND: Neural components of the fibrous filum terminale (FT) are well known but
are considered as embryonic remnants without functionality. OBJECTIVE: To investigate the …

The pathology of lumbosacral lipomas: macroscopic and microscopic disparity have implications for embryogenesis and mode of clinical deterioration

V Jones, V Wykes, N Cohen, D Thompson… - …, 2018 - Wiley Online Library
Aims Lumbosacral lipomas (LSL) are congenital disorders of the terminal spinal cord region
that have the potential to cause significant spinal cord dysfunction in children. They are of …

[HTML][HTML] Surgical histopathology of a filar anomaly as an additional tethering element associated with closed spinal dysraphism of primary neurulation failure

T Morioka, N Murakami, SO Suzuki… - Surgical Neurology …, 2021 - ncbi.nlm.nih.gov
Background: Closed spinal dysraphism of primary neurulation failure could be associated
with filar anomalies, such as filar lipoma or thickened and tight filum terminale (TFT) …

The Surgical Histopathology of the Filum Terminale: Findings from a Large Series of Patients with Tethered Cord Syndrome

H Abdulrazeq, OP Leary, OY Tang, H Karimi… - Journal of Clinical …, 2023 - mdpi.com
This study investigated the prevalence of embryonic and connective tissue elements in the
filum terminale (FT) of patients with tethered cord syndrome (TCS), examining both typical …

The discrepancy in triggered electromyography responses between fatty filum and normal filum terminale

Y Cai, R Wang, J Wang, Q Zhan, M Wei, B Xiao… - BMC surgery, 2024 - Springer
Background Functional role of filum terminale (FT) was not well studied though it contains
structure basis for nerve impulse conduction. We aimed to explore the possible functions of …

Fatty filum terminale (FFT) as a secondary tethering element in children with closed spinal dysraphism

A Gupta, V Rajshekhar - Child's Nervous System, 2018 - Springer
Purpose The purpose of this study was to assess the prevalence of FFT as an additional
tethering element in children operated for closed spinal dysraphism, where FFT was not the …

[HTML][HTML] Glial fibrillary acidic protein immunopositive neuroglial tissues with or without ependyma-lined canal in spinal lipoma of filar type: Relationship with retained …

N Murakami, T Morioka, A Kurogi… - Surgical Neurology …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Retained medullary cord (RMC) and filar lipomas are believed to originate from
secondary neurulation failure; filar lipomas are reported to histopathologically contain a …

Structures of filum terminale and characteristics of ependymal cells of its central canal in rats

N Nakano, K Kanekiyo, Y Yamada, M Tamachi… - Brain Research, 2019 - Elsevier
The filum terminale (FT) is a potential source of ependymal cells for transplantation. The
present study was performed to clarify the characteristics of ependymal cells of the central …