Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies

P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …

Stem cell therapy for chronic ischaemic heart disease and congestive heart failure

SA Fisher, C Doree, A Mathur… - Cochrane Database …, 2016 - cochranelibrary.com
Background A promising approach to the treatment of chronic ischaemic heart disease and
congestive heart failure is the use of stem cells. The last decade has seen a plethora of …

[HTML][HTML] Recent advances in the diagnosis and treatment of acute myocardial infarction

K Reddy, A Khaliq, RJ Henning - World journal of cardiology, 2015 - ncbi.nlm.nih.gov
Abstract The Third Universal Definition of Myocardial Infarction (MI) requires cardiac
myocyte necrosis with an increase and/or a decrease in a patient's plasma of cardiac …

Adult bone marrow–derived cells for cardiac repair: a systematic review and meta-analysis

A Abdel-Latif, R Bolli, IM Tleyjeh… - Archives of internal …, 2007 - jamanetwork.com
Background The results from small clinical studies suggest that therapy with adult bone
marrow (BM)–derived cells (BMCs) reduces infarct size and improves left ventricular function …

Postischemic revascularization: from cellular and molecular mechanisms to clinical applications

JS Silvestre, DM Smadja, BI Levy - Physiological reviews, 2013 - journals.physiology.org
After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review

E Martin-Rendon, SJ Brunskill, CJ Hyde… - European heart …, 2008 - academic.oup.com
Aims To provide systematic assessment of the safety and efficacy of autologous bone
marrow-derived stem cell (BMSC) transplantation in acute myocardial infarction (AMI) based …

Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of …

MJ Lipinski, GGL Biondi-Zoccai, A Abbate… - Journal of the American …, 2007 - jacc.org
Objectives: We aimed to perform a meta-analysis of clinical trials on intracoronary cell
therapy after acute myocardial infarction (AMI). Background: Intracoronary cell therapy …

Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant diseases

RK Burt, Y Loh, W Pearce, N Beohar, WG Barr, R Craig… - Jama, 2008 - jamanetwork.com
Context Stem cell therapy is rapidly developing and has generated excitement and promise
as well as confusion and at times contradictory results in the lay and scientific literature …

Stem cell treatment for acute myocardial infarction

SA Fisher, H Zhang, C Doree, A Mathur… - Cochrane Database …, 2015 - cochranelibrary.com
Background Cell transplantation offers a potential therapeutic approach to the repair and
regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI) …

[HTML][HTML] Surfing the clinical trials of mesenchymal stem cell therapy in ischemic cardiomyopathy

I Razeghian-Jahromi, AG Matta, R Canitrot… - Stem Cell Research & …, 2021 - Springer
While existing remedies failed to fully address the consequences of heart failure, stem cell
therapy has been introduced as a promising approach. The present review is a …