Nanodrugs, which utilise nanomaterials in disease prevention and therapy, have attracted
considerable interest since their initial conceptualisation in the 1990s. Substantial efforts …

Zwitterionic polymers exhibit excellent nonfouling performance due to their strong surface
hydrations. However, salt molecules may severely reduce the surface hydrations of typical …

Nanoparticles (NPs) inevitably interact with proteins upon exposure to biological fluids,
leading to the formation of an adsorption layer known as the “protein corona”. This corona …

Targeting ligands are conjugated onto nanoparticles to increase their selectivity for diseased
cells. However, they become covered by serum proteins which prevent them from binding to …

Particle size might affect the inhibition behaviors of gold nanoparticles (AuNPs) on enzyme
activity by influencing the density of binding sites (ρ), the association constant (K a), the …

Matrix effects limit the application of surface-enhanced Raman scattering (SERS) technology
in the field of food safety. This study elucidated it from the perspective of protein corona by …

Despite the obvious advantages of gold nanoparticles for biomedical applications,
controversial and incomplete toxicological data hamper their widespread use. Here, we …

The size or the curvature of nanoparticles (NPs) plays an important role in regulating the
composition of the protein corona. However, the molecular mechanisms of how curvature …

Zwitterionic polymers have emerged as a class of highly effective ultralow fouling materials
for critical marine coating and biomedical applications. The recently developed …

Abstract Abstract Gold nanoparticles (AuNPs) are promising materials for many
bioapplications. However, upon contacting with biological media, AuNPs undergo changes …