Cancer genomic, transcriptomic, and proteomic profiling has generated extensive data that
necessitate the development of tools for its analysis and dissemination. We developed …

Mass-spectrometry-based proteomic data on human tumors—combined with corresponding
multi-omics data—present opportunities for systematic and pan-cancer proteogenomic …

Recent technological advancements in mass spectrometry (MS)‐based proteomics
technologies have accelerated its application to study greater and greater numbers of …

Background Previous studies have shown that the N6-methyladenosine (m6A) modification
enhances the binding ability of mRNAs/long noncoding RNAs (lncRNAs) to microRNAs …

Both proteome and transcriptome data can help assess the relevance of non-coding somatic
mutations in cancer. Here, we combine mass spectrometry-based proteomics data with …

Clinical Bioinformatics is a knowledge framework required to interpret data of medical
interest via computational methods. This area became of dramatic importance in precision …

Human methyltransferase-like (METTL) proteins transfer methyl groups to nucleic acids,
proteins, lipids, and other small molecules, subsequently playing important roles in various …

Endometrial cancer is the most common gynaecological malignancy in developed countries.
Over 382,000 new cases were diagnosed worldwide in 2018, and its incidence and mortality …

The vast amount of gene expression profiling data of bulk tumors and cell lines available in
the public domain represents a tremendous resource. For any major cancer type, expression …

The global impact of somatic structural variants (SVs) on gene regulation in advanced
tumors with complex treatment histories has been mostly uncharacterized. Here, using …