Silicon‐substituted xanthene dyes, with Si in place of the O atom at the xanthene 10‐
position, are practically useful as far‐red to near‐infrared fluorophores. Many fluorescent …

Intracellular Ca 2+ fluxes are dynamically controlled by the co-involvement of multiple
organellar pools of stored Ca 2+. Endolysosomes are emerging as physiologically critical …

Enhanced neuronal activity in the brain triggers a local increase in blood flow, termed
functional hyperemia, via several mechanisms, including calcium (Ca2+) signaling in …

This paper describes the design and synthesis of a photostable, far-red to near-infrared
(NIR) platform for optical voltage sensing. We developed a new, sulfonated silicon …

Localized subcellular changes in Ca 2+ serve as important cellular signaling elements,
regulating processes as diverse as neuronal excitability and gene expression. Studies of …

Herein, a single highly selective DNA nanoprobe was designed and created for the real-time
imaging and simultaneous quantification of two kinds of biological species using Ca2+ and …

We introduce a family of bright, rhodamine-based calcium indicators with tuneable affinities
and colors. The indicators can be specifically localized to different cellular compartments …

We introduce a selective and cell-permeable calcium sensor for photoacoustics (CaSPA), a
versatile imaging technique that allows for fast volumetric mapping of photoabsorbing …

Non-invasive observation of spatiotemporal activity of large neural populations distributed
over entire brains is a longstanding goal of neuroscience. We developed a volumetric …

In vivo Ca2+ imaging of neuronal populations in deep cortical layers has remained a major
challenge, as the recording depth of two-photon microscopy is limited because of the …