Abstract Mitochondria-associated membranes (MAM), physical platforms that enable
communication between mitochondria and the endoplasmic reticulum (ER), are enriched …

Calsequestrin (CASQ) was discovered in rabbit skeletal muscle tissues in 1971 and has
been considered simply a passive Ca2+-buffering protein in the sarcoplasmic reticulum (SR) …

Abstract Background Local injection of BaCl 2 is an established model of acute injury to
study the regeneration of skeletal muscle. However, the mechanism by which BaCl 2 causes …

Ca2+ itself or Ca2+-dependent signaling pathways play fundamental roles in various
cellular processes from cell growth to death. The most representative example can be found …

Atrial fibrillation (AF) is the most frequent arrhythmia in adults. The prevalence and incidence
of AF is going to increase substantially over the next few decades. Because AF increases …

Human life expectancy has markedly increased over the past hundred years. Consequently,
the percentage of elderly people is increasing. Aging and sarcopenic changes in skeletal …

A variety of internal and external factors such as exercise, nutrition, inflammation, and
cancer‐associated cachexia affect the regulation of skeletal muscle mass. Because skeletal …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease
characterized by selective death of motor neurons. Mutations in Cu, Zn-superoxide …

Histidine-containing dipeptides (HCDs) are abundantly expressed in striated muscles.
Although important properties have been ascribed to HCDs, including H+ buffering …

Tubular Aggregate Myopathy (TAM) is a hereditary ultra-rare muscle disorder characterized
by muscle weakness and cramps or myasthenic features. Biopsies from TAM patients show …