Long noncoding RNAs and repetitive elements: junk or intimate evolutionary partners?
Our recent ability to sequence entire genomes, along with all of their transcribed RNAs, has
led to the surprising finding that only∼ 1% of the human genome is used to encode proteins …
led to the surprising finding that only∼ 1% of the human genome is used to encode proteins …
A single cell but many different transcripts: a journey into the world of long non-coding RNAs
E Alessio, RS Bonadio, L Buson, F Chemello… - International journal of …, 2020 - mdpi.com
In late 2012 it was evidenced that most of the human genome is transcribed but only a small
percentage of the transcripts are translated. This observation supported the importance of …
percentage of the transcripts are translated. This observation supported the importance of …
[HTML][HTML] A single-cell transcriptomic atlas of the adult Drosophila ventral nerve cord
The Drosophila ventral nerve cord (VNC) receives and processes descending signals from
the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory …
the brain to produce a variety of coordinated locomotor outputs. It also integrates sensory …
Genomic and functional conservation of lncRNAs: lessons from flies
Over the last decade, the increasing interest in long non-coding RNAs (lncRNAs) has led to
the discovery of these transcripts in multiple organisms. LncRNAs tend to be specifically …
the discovery of these transcripts in multiple organisms. LncRNAs tend to be specifically …
[HTML][HTML] Chromatin gene-gene loops support the cross-regulation of genes with related function
T Pollex, R Marco-Ferreres, L Ciglar, Y Ghavi-Helm… - Molecular Cell, 2024 - cell.com
Chromatin loops between gene pairs have been observed in diverse contexts in both flies
and vertebrates. Combining high-resolution Capture-C, DNA fluorescence in situ …
and vertebrates. Combining high-resolution Capture-C, DNA fluorescence in situ …
Insights into the Functions of LncRNAs in Drosophila
Long non-coding RNAs (lncRNAs) are a class of non-coding RNAs longer than 200
nucleotides (nt). LncRNAs have high spatiotemporal specificity, and secondary structures …
nucleotides (nt). LncRNAs have high spatiotemporal specificity, and secondary structures …
Long non-coding RNAs in insects
C Choudhary, S Sharma, KK Meghwanshi, S Patel… - Animals, 2021 - mdpi.com
Simple Summary Long-non-coding RNAs (lncRNAs) are transcripts of more than 200
nucleotides, which lack protein-coding potential. LncRNAs have been well characterized in …
nucleotides, which lack protein-coding potential. LncRNAs have been well characterized in …
REDfly: an integrated knowledgebase for insect regulatory genomics
SVE Keränen, A Villahoz-Baleta, AE Bruno, MS Halfon - Insects, 2022 - mdpi.com
Simple Summary Understanding how genes are regulated is a vital area of current
biological research and a crucial adjunct to ongoing efforts to sequence entire genomes …
biological research and a crucial adjunct to ongoing efforts to sequence entire genomes …
Iron accumulation regulates osteoblast apoptosis through lncRNA XIST/miR‐758‐3p/caspase 3 axis leading to osteoporosis
H Liu, YW Wang, WD Chen, HH Dong, YJ Xu - IUBMB life, 2021 - Wiley Online Library
Postmenopausal osteoporosis (PMOP) is mainly caused by multiple factors. Recent studies
have suggested that iron accumulation (IA) was closely related to PMOP. However, the …
have suggested that iron accumulation (IA) was closely related to PMOP. However, the …
Dissecting the transcriptional regulatory networks of promoter-associated noncoding RNAs in development and cancer
L Chellini, V Frezza, MP Paronetto - Journal of Experimental & Clinical …, 2020 - Springer
In-depth analysis of global RNA sequencing has enabled a comprehensive overview of
cellular transcriptomes and revealed the pervasive transcription of divergent RNAs from …
cellular transcriptomes and revealed the pervasive transcription of divergent RNAs from …