The roles of water in the protein matrix: a largely untapped resource for drug discovery
F Spyrakis, MH Ahmed, AS Bayden… - Journal of medicinal …, 2017 - ACS Publications
The value of thoroughly understanding the thermodynamics specific to a drug
discovery/design study is well known. Over the past decade, the crucial roles of water …
discovery/design study is well known. Over the past decade, the crucial roles of water …
Assessment of catalytic, antimicrobial and molecular docking analysis of starch-grafted polyacrylic acid doped BaO nanostructures
The removal of cationic dyes from water has received a great attention of researchers
considering their influence on environment and ecosystem. In current work, starch-grafted …
considering their influence on environment and ecosystem. In current work, starch-grafted …
Synthesis of curcuma longa doped cellulose grafted hydrogel for catalysis, bactericidial and insilico molecular docking analysis
Curcumin (diferuloylmethane), the primary curcuminoid in turmeric rhizome, has been
acknowledged as a bioactive compound for numerous pharmacological activities …
acknowledged as a bioactive compound for numerous pharmacological activities …
[HTML][HTML] Bacterial enoyl-reductases: the ever-growing list of fabs, their mechanisms and inhibition
FSM Hopf, CD Roth, EV de Souza, L Galina… - Frontiers in …, 2022 - frontiersin.org
Enoyl-ACP reductases (ENRs) are enzymes that catalyze the last step of the elongation
cycle during fatty acid synthesis. In recent years, new bacterial ENR types were discovered …
cycle during fatty acid synthesis. In recent years, new bacterial ENR types were discovered …
[HTML][HTML] Antimicrobial potential and rhodamine B dye degradation using graphitic carbon nitride and polyvinylpyrrolidone doped bismuth tungstate supported with in …
The environmental-friendly hydrothermal method has been carried out to synthesize
Bi2WO6 and g-C3N4/PVP doped Bi2WO6 nanorods (NRs) by incorporating different …
Bi2WO6 and g-C3N4/PVP doped Bi2WO6 nanorods (NRs) by incorporating different …
[HTML][HTML] Comparative study of selenides and tellurides of transition metals (Nb and Ta) with respect to its catalytic, antimicrobial, and molecular docking performance
The present research is a comparative study that reports an economical and accessible
method to synthesize niobium (Nb) and Tantalum (Ta) selenides and tellurides with useful …
method to synthesize niobium (Nb) and Tantalum (Ta) selenides and tellurides with useful …
Biological evaluation, proposed molecular mechanism through docking and molecular dynamic simulation of derivatives of chitosan
RE Malekshah, F Shakeri, M Aallaei, M Hemati… - International Journal of …, 2021 - Elsevier
We synthesized Schiff base and its complexes derivatives of chitosan (CS) in order to
develop antibiotic compounds based on functionalized-chitosan against gram-positive and …
develop antibiotic compounds based on functionalized-chitosan against gram-positive and …
[HTML][HTML] Molecular modelling study and antibacterial evaluation of diphenylmethane derivatives as potential fabi inhibitors
The need for new antibiotics has become a major worldwide challenge as bacterial strains
keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier …
keep developing resistance to the existing drugs at an alarming rate. Enoyl-acyl carrier …
The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl‐Acyl Carrier Protein Binding Site of FabI
CD Fage, T Lathouwers, M Vanmeert… - Angewandte Chemie …, 2020 - Wiley Online Library
The enoyl‐acyl carrier protein reductase enzyme FabI is essential for fatty acid biosynthesis
in Staphylococcus aureus and represents a promising target for the development of novel …
in Staphylococcus aureus and represents a promising target for the development of novel …
Targeting multidrug resistant Staphylococcus aureus with cationic chlorpromazine‐peptide conjugates
Antimicrobial resistance is a serious public health risk. Its severity is fueled on an
unprecedented scale, necessitating the demand for novel antimicrobial scaffolds aimed at …
unprecedented scale, necessitating the demand for novel antimicrobial scaffolds aimed at …