Cognitive impairment in people living with HIV: consensus recommendations for a new approach

S Nightingale, B Ances, P Cinque, A Dravid… - Nature Reviews …, 2023 - nature.com
Current approaches to classifying cognitive impairment in people living with HIV can
overestimate disease burden and lead to ambiguity around disease mechanisms. The 2007 …

The prevalence of Frascati-criteria-based HIV-associated neurocognitive disorder (HAND) in HIV-infected adults: a systematic review and meta-analysis

J Wei, J Hou, B Su, T Jiang, C Guo, W Wang… - Frontiers in …, 2020 - frontiersin.org
Background: The HIV associated mortality is decreasing in most countries due to the
widespread use of antiretroviral therapy. However, HIV-associated neurocognitive disorder …

Global prevalence and burden of HIV-associated neurocognitive disorder: a meta-analysis

Y Wang, M Liu, Q Lu, M Farrell, JM Lappin, J Shi, L Lu… - Neurology, 2020 - AAN Enterprises
Objective To characterize the prevalence and burden of HIV-associated neurocognitive
disorder (HAND) and assess associated factors in the global population with HIV. Methods …

HIV-associated neurocognitive disorder

DB Clifford, BM Ances - The Lancet infectious diseases, 2013 - thelancet.com
Neurological involvement in HIV is often associated with cognitive impairment. Although
severe and progressive neurocognitive impairment has become rare in HIV clinics in the era …

Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline

I Grant, DR Franklin Jr, R Deutsch, SP Woods, F Vaida… - Neurology, 2014 - AAN Enterprises
Objective: While HIV-associated neurocognitive disorders (HAND) remain prevalent despite
combination antiretroviral therapy (CART), the clinical relevance of asymptomatic …

Controversies in HIV-associated neurocognitive disorders

S Nightingale, A Winston, S Letendre… - The Lancet …, 2014 - thelancet.com
Cross-sectional studies show that around half of individuals infected with HIV-1 have some
degree of cognitive impairment despite the use of antiretroviral drugs. However, prevalence …

Cognitive disorders in people living with HIV

A Winston, S Spudich - The Lancet HIV, 2020 - thelancet.com
High rates of cognitive disorders in antiretroviral-treated people living with HIV have been
described worldwide. The exact prevalence of such cognitive disorders is determined by the …

COP27 climate change conference: urgent action needed for Africa and the world

L Atwoli, GE Erhabor, AA Gbakima… - The Lancet Infectious …, 2023 - thelancet.com
The primary focus of climate summits remains to rapidly reduce emissions so that global
temperature rises are kept to below 1· 5 C. This will limit the harm. But, for Africa and other …

Important role of microglia in HIV-1 associated neurocognitive disorders and the molecular pathways implicated in its pathogenesis

A Borrajo, C Spuch, MA Penedo, JM Olivares… - Annals of …, 2021 - Taylor & Francis
The development of effective combined anti-retroviral therapy (cART) led to a significant
reduction in the death rate associated with human immunodeficiency virus type 1 (HIV-1) …

Cognitive impairment in people living with HIV in the ART era: a review

K Alford, JH Vera - British medical bulletin, 2018 - academic.oup.com
Background Cognitive disorders are a common issue impacting those living with human
immunodeficiency virus (HIV). Effective antiretroviral treatment has lessened the severity but …