[HTML][HTML] CLIP and complementary methods
RNA molecules start assembling into ribonucleoprotein (RNP) complexes during
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
transcription. Dynamic RNP assembly, largely directed by cis-acting elements on the RNA …
[HTML][HTML] Widespread 8-oxoguanine modifications of miRNA seeds differentially regulate redox-dependent cancer development
Oxidative stress contributes to tumourigenesis by altering gene expression. One
accompanying modification, 8-oxoguanine (o8G) can change RNA–RNA interactions via …
accompanying modification, 8-oxoguanine (o8G) can change RNA–RNA interactions via …
[HTML][HTML] Position-specific oxidation of miR-1 encodes cardiac hypertrophy
In pathophysiology, reactive oxygen species oxidize biomolecules that contribute to disease
phenotypes. One such modification, 8-oxoguanine (o8G), is abundant in RNA but its …
phenotypes. One such modification, 8-oxoguanine (o8G), is abundant in RNA but its …
[PDF][PDF] Galaxy CLIP-Explorer: a web server for CLIP-Seq data analysis
Background Post-transcriptional regulation via RNA-binding proteins plays a fundamental
role in every organism, but the regulatory mechanisms lack important understanding …
role in every organism, but the regulatory mechanisms lack important understanding …
LNRLMI: Linear neighbour representation for predicting lncRNA‐miRNA interactions
LncRNA and miRNA are key molecules in mechanism of competing endogenous RNAs
(ceRNA), and their interactions have been discovered with important roles in gene …
(ceRNA), and their interactions have been discovered with important roles in gene …
AGO CLIP-based imputation of potent siRNA sequences targeting SARS-CoV-2 with antifibrotic miRNA-like activity
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is associated with fatal pulmonary fibrosis. Small …
syndrome coronavirus 2 (SARS-CoV-2), is associated with fatal pulmonary fibrosis. Small …
AGO-accessible anticancer siRNAs designed with synergistic miRNA-like activity
Small interfering RNAs (siRNAs) therapeutically induce RNA interference (RNAi) of disease-
causing genes, but they also silence hundreds of seed-matched off-targets as behaving …
causing genes, but they also silence hundreds of seed-matched off-targets as behaving …
Genome-wide cross-cancer analysis illustrates the critical role of bimodal miRNA in patient survival and drug responses to PI3K inhibitors
Heterogeneity of cancer means many tumorigenic genes are only aberrantly expressed in a
subset of patients and thus follow a bimodal distribution, having two modes of expression …
subset of patients and thus follow a bimodal distribution, having two modes of expression …
Prediction of Circular RNA-RBP Binding Sites Based on Multi-source Features and Cascade Forest
Y Guo, Q Meng, Q Zhang, X Xu - International Conference on Intelligent …, 2024 - Springer
Circular RNAs (circRNAs) are a non-coding RNAs with a special circular structure. They play
an important role in gene regulation and interact with RNA-binding proteins (RBPs) to …
an important role in gene regulation and interact with RNA-binding proteins (RBPs) to …
Computational models to infer regulators of gene expression for high-throughput data
M Katsantoni - 2023 - edoc.unibas.ch
Ever since the formulation of the central dogma of biology, the focus was shifted into how the
various steps up to the protein formation are regulated. RNA-binding proteins (RBPs) have …
various steps up to the protein formation are regulated. RNA-binding proteins (RBPs) have …